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Page 1
Showing results for epo non ea
Search for Eponon EA instead (1 results)
Effect of empagliflozin on ectopic fat stores and myocardial energetics in type 2 diabetes: the EMPACEF study.
Gaborit B, Ancel P, Abdullah AE, Maurice F, Abdesselam I, Calen A, Soghomonian A, Houssays M, Varlet I, Eisinger M, Lasbleiz A, Peiretti F, Bornet CE, Lefur Y, Pini L, Rapacchi S, Bernard M, Resseguier N, Darmon P, Kober F, Dutour A. Gaborit B, et al. Cardiovasc Diabetol. 2021 Mar 1;20(1):57. doi: 10.1186/s12933-021-01237-2. Cardiovasc Diabetol. 2021. PMID: 33648515 Free PMC article. Clinical Trial.
Compared to placebo, T2D patients treated with EMPA significantly lost weight (- 2.6 kg [- 1.2; - 3.7]) and improved their HbA1c by 0.88 0.74%. Hematocrit and EPO levels were significantly increased in the EMPA group compared to placebo (p < 0.0001, p = 0.041). ...
Compared to placebo, T2D patients treated with EMPA significantly lost weight (- 2.6 kg [- 1.2; - 3.7]) and improved their HbA1c by 0.88 0.7 …
Aquaporin-1 plays a key role in erythropoietin-induced endothelial cell migration.
Maltaneri RE, Schiappacasse A, Chamorro ME, Nesse AB, Vittori DC. Maltaneri RE, et al. Biochim Biophys Acta Mol Cell Res. 2020 Jan;1867(1):118569. doi: 10.1016/j.bbamcr.2019.118569. Epub 2019 Oct 30. Biochim Biophys Acta Mol Cell Res. 2020. PMID: 31676353 Free article.
Inhibition of AQP-1 with either mercury ions (Hg(2+)) or a specific siRNA led to an impaired migration of EA.hy926 endothelial cells exposed to Epo (wound-healing assays). ...Worthy of note, carbamylated erythropoietin (cEpo), the non-erythropoietic and no …
Inhibition of AQP-1 with either mercury ions (Hg(2+)) or a specific siRNA led to an impaired migration of EA.hy926 endothelial cells …
Erythropoietin and myocardial protection: what's new?
Joyeux-Faure M, Godin-Ribuot D, Ribuot C. Joyeux-Faure M, et al. Fundam Clin Pharmacol. 2005 Aug;19(4):439-46. doi: 10.1111/j.1472-8206.2005.00347.x. Fundam Clin Pharmacol. 2005. PMID: 16011730 Review.
Erythropoietin (EPO), the principal hematopoietic cytokine produced by the kidney and the liver in fetuses, regulates mammalian erythropoiesis and exhibits diverse cellular effects in non-hematopoietic tissues. The introduction of recombinant human EPO (rhEPO …
Erythropoietin (EPO), the principal hematopoietic cytokine produced by the kidney and the liver in fetuses, regulates mammalian eryth …
Novel erythropoietin-based therapeutic candidates with extra N-glycan sites that block hematopoiesis but preserve neuroplasticity.
Bürgi M, Aparicio GI, Dorella A, Kratje R, Scorticati C, Oggero M. Bürgi M, et al. Biotechnol J. 2021 May;16(5):e2000455. doi: 10.1002/biot.202000455. Epub 2021 Feb 9. Biotechnol J. 2021. PMID: 33471394
Human erythropoietin (hEPO) has been clinically used because of its neurotrophic and cytoprotective properties. However, the erythropoietic activity (EA) should be considered as a side effect. Some analogs like non-sialylated EPO, carbamylated EPO, or …
Human erythropoietin (hEPO) has been clinically used because of its neurotrophic and cytoprotective properties. However, the erythropoietic …
Electroacupuncture attenuates ischemic injury after stroke and promotes angiogenesis via activation of EPO mediated Src and VEGF signaling pathways.
Wang L, Sheng G, Cui J, Yao Y, Bai X, Chen F, Yu W. Wang L, et al. PLoS One. 2022 Sep 15;17(9):e0274620. doi: 10.1371/journal.pone.0274620. eCollection 2022. PLoS One. 2022. PMID: 36108080 Free PMC article.
Taken together, our findings showed that EA at the GV26 acupoint can significantly attenuate ischemic injury after stroke and promote angiogenesis via activation of EPO-mediated Src and VEGF signaling pathways. Besides, the upregulation of VEGF may also be associate …
Taken together, our findings showed that EA at the GV26 acupoint can significantly attenuate ischemic injury after stroke and promote …
Expression of erythropoietin and erythropoietin receptor in non-small cell lung carcinomas.
Dagnon K, Pacary E, Commo F, Antoine M, Bernaudin M, Bernaudin JF, Callard P. Dagnon K, et al. Clin Cancer Res. 2005 Feb 1;11(3):993-9. Clin Cancer Res. 2005. PMID: 15709164
This study, in non-small cell lung carcinoma, was designed to investigate the previously unreported expression of Epo and Epo-R as well as hypoxia-inducible factor-1alpha (HIF-1alpha), which is known to control Epo expression. ...HIF-1alpha was immunol …
This study, in non-small cell lung carcinoma, was designed to investigate the previously unreported expression of Epo and E …
Mechanism of erythropoietin regulation by angiotensin II.
Kim YC, Mungunsukh O, McCart EA, Roehrich PJ, Yee DK, Day RM. Kim YC, et al. Mol Pharmacol. 2014 Jun;85(6):898-908. doi: 10.1124/mol.113.091157. Epub 2014 Apr 2. Mol Pharmacol. 2014. PMID: 24695083
Erythropoietin (EPO) is the primary regulator of red blood cell development. Although hypoxic regulation of EPO has been extensively studied, the mechanism(s) for basal regulation of EPO are not well understood. ...We further investigated the signaling mechan …
Erythropoietin (EPO) is the primary regulator of red blood cell development. Although hypoxic regulation of EPO has been exten …
Pharmacological, but not genetic, alteration of neural Epo modifies the CO(2)/H(+) central chemosensitivity in postnatal mice.
Laouafa S, Perrin-Terrin AS, Jeton F, Elliot-Portal E, Tam R, Bodineau L, Voituron N, Soliz J. Laouafa S, et al. Respir Physiol Neurobiol. 2017 Aug;242:73-79. doi: 10.1016/j.resp.2017.04.003. Epub 2017 Apr 8. Respir Physiol Neurobiol. 2017. PMID: 28396201
Cerebral erythropoietin (Epo) plays a crucial role for respiratory control in newborn rodents. We showed previously that soluble Epo receptor (sEpoR: an Epo antagonist) reduces basal ventilation and hypoxic hyperventilation at postnatal day 10 (P10) and in ad …
Cerebral erythropoietin (Epo) plays a crucial role for respiratory control in newborn rodents. We showed previously that soluble E …
Role of protein tyrosine phosphatase 1B (PTP1B) in the increased sensitivity of endothelial cells to a promigratory effect of erythropoietin in an inflammatory environment.
Chamorro ME, Maltaneri R, Schiappacasse A, Nesse A, Vittori D. Chamorro ME, et al. Biol Chem. 2020 Sep 25;401(10):1167-1180. doi: 10.1515/hsz-2020-0136. Biol Chem. 2020. PMID: 32386183
With the aim of investigating possible modifications in the activity of erythropoietin (Epo) in an inflammatory environment, we found that Epo at a non-promigratory concentration was capable of stimulating EA.hy926 endothelial cell migration when TNF-a …
With the aim of investigating possible modifications in the activity of erythropoietin (Epo) in an inflammatory environment, we found …
The central chemosensitivity is not altered by cerebral erythropoietin.
Ballot O, Laouafa S, Elliot-Portal E, Tam R, Voituron N, Joseph V, Soliz J. Ballot O, et al. Neurosci Lett. 2015 Nov 16;609:63-8. doi: 10.1016/j.neulet.2015.10.026. Epub 2015 Oct 17. Neurosci Lett. 2015. PMID: 26472708
The injection of soluble Epo receptor (sEpoR; the natural EpoR competitor to bind Epo) via the cisterna magna (ICI: intra-cisternal injection) decreases basal ventilation in adult and newborn mice. Moreover, sEpoR induces respiratory depression in adult and newborn …
The injection of soluble Epo receptor (sEpoR; the natural EpoR competitor to bind Epo) via the cisterna magna (ICI: intra-cist …
28 results