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Quality attributes of recombinant therapeutic proteins: an assessment of impact on safety and efficacy as part of a quality by design development approach.
Biotechnol Prog. 2012 May-Jun;28(3):608-22. doi: 10.1002/btpr.1548. Epub 2012 May 2.
Biotechnol Prog. 2012.
PMID: 22473974
Review.
Application of Quality by Design to the characterization of the cell culture process of an Fc-Fusion protein.
Rouiller Y, Solacroup T, Deparis V, Barbafieri M, Gleixner R, Broly H, Eon-Duval A.
Rouiller Y, et al. Among authors: eon duval a.
Eur J Pharm Biopharm. 2012 Jun;81(2):426-37. doi: 10.1016/j.ejpb.2012.02.018. Epub 2012 Mar 9.
Eur J Pharm Biopharm. 2012.
PMID: 22426134
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Application of the quality by design approach to the drug substance manufacturing process of an Fc fusion protein: towards a global multi-step design space.
Eon-duval A, Valax P, Solacroup T, Broly H, Gleixner R, Strat CL, Sutter J.
Eon-duval A, et al.
J Pharm Sci. 2012 Oct;101(10):3604-18. doi: 10.1002/jps.23273. Epub 2012 Jul 20.
J Pharm Sci. 2012.
PMID: 22821774
Item in Clipboard
Precipitation of RNA impurities with high salt in a plasmid DNA purification process: use of experimental design to determine reaction conditions.
Eon-Duval A, Gumbs K, Ellett C.
Eon-Duval A, et al.
Biotechnol Bioeng. 2003 Sep 5;83(5):544-53. doi: 10.1002/bit.10704.
Biotechnol Bioeng. 2003.
PMID: 12827696
Item in Clipboard
Removal of RNA impurities by tangential flow filtration in an RNase-free plasmid DNA purification process.
Eon-Duval A, MacDuff RH, Fisher CA, Harris MJ, Brook C.
Eon-Duval A, et al.
Anal Biochem. 2003 May 1;316(1):66-73. doi: 10.1016/s0003-2697(03)00050-2.
Anal Biochem. 2003.
PMID: 12694728
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Purification of pharmaceutical-grade plasmid DNA by anion-exchange chromatography in an RNase-free process.
Eon-Duval A, Burke G.
Eon-Duval A, et al.
J Chromatogr B Analyt Technol Biomed Life Sci. 2004 May 25;804(2):327-35. doi: 10.1016/j.jchromb.2004.01.033.
J Chromatogr B Analyt Technol Biomed Life Sci. 2004.
PMID: 15081927
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Genetic engineering of α2,6-sialyltransferase in recombinant CHO cells and its effects on the sialylation of recombinant interferon-γ.
Monaco L, Marc A, Eon-Duval A, Acerbis G, Distefano G, Lamotte D, Engasser JM, Soria M, Jenkins N.
Monaco L, et al. Among authors: eon duval a.
Cytotechnology. 1996 Jan;22(1-3):197-203. doi: 10.1007/BF00353939.
Cytotechnology. 1996.
PMID: 22358930
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