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TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models.
Wilson EN, Wang C, Swarovski MS, Zera KA, Ennerfelt HE, Wang Q, Chaney A, Gauba E, Ramos Benitez JA, Le Guen Y, Minhas PS, Panchal M, Tan YJ, Blacher E, A Iweka C, Cropper H, Jain P, Liu Q, Mehta SS, Zuckerman AJ, Xin M, Umans J, Huang J, Durairaj AS, Serrano GE, Beach TG, Greicius MD, James ML, Buckwalter MS, McReynolds MR, Rabinowitz JD, Andreasson KI. Wilson EN, et al. Among authors: ennerfelt he. Nat Neurosci. 2024 May;27(5):873-885. doi: 10.1038/s41593-024-01610-w. Epub 2024 Mar 27. Nat Neurosci. 2024. PMID: 38539014 Free PMC article.
Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis.
Bolte AC, Dutta AB, Hurt ME, Smirnov I, Kovacs MA, McKee CA, Ennerfelt HE, Shapiro D, Nguyen BH, Frost EL, Lammert CR, Kipnis J, Lukens JR. Bolte AC, et al. Among authors: ennerfelt he. Nat Commun. 2020 Sep 10;11(1):4524. doi: 10.1038/s41467-020-18113-4. Nat Commun. 2020. PMID: 32913280 Free PMC article.
The role of innate immunity in Alzheimer's disease.
Ennerfelt HE, Lukens JR. Ennerfelt HE, et al. Immunol Rev. 2020 Sep;297(1):225-246. doi: 10.1111/imr.12896. Epub 2020 Jun 26. Immunol Rev. 2020. PMID: 32588460 Free PMC article. Review.
AIM2 inflammasome surveillance of DNA damage shapes neurodevelopment.
Lammert CR, Frost EL, Bellinger CE, Bolte AC, McKee CA, Hurt ME, Paysour MJ, Ennerfelt HE, Lukens JR. Lammert CR, et al. Among authors: ennerfelt he. Nature. 2020 Apr;580(7805):647-652. doi: 10.1038/s41586-020-2174-3. Epub 2020 Apr 8. Nature. 2020. PMID: 32350463 Free PMC article.