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Implications of the Conformationally Flexible, Macrocyclic Structure of the First-Generation, Direct-Acting Anti-Viral Paritaprevir on Its Solid Form Complexity and Chameleonic Behavior.
Sheikh AY, Mattei A, Miglani Bhardwaj R, Hong RS, Abraham NS, Schneider-Rauber G, Engstrom KM, Diwan M, Henry RF, Gao Y, Juarez V, Jordan E, DeGoey DA, Hutchins CW. Sheikh AY, et al. Among authors: engstrom km. J Am Chem Soc. 2021 Oct 27;143(42):17479-17491. doi: 10.1021/jacs.1c06837. Epub 2021 Oct 12. J Am Chem Soc. 2021. PMID: 34637297
Discovery of adamantane ethers as inhibitors of 11beta-HSD-1: Synthesis and biological evaluation.
Patel JR, Shuai Q, Dinges J, Winn M, Pliushchev M, Fung S, Monzon K, Chiou W, Wang J, Pan L, Wagaw S, Engstrom K, Kerdesky FA, Longenecker K, Judge R, Qin W, Imade HM, Stolarik D, Beno DW, Brune M, Chovan LE, Sham HL, Jacobson P, Link JT. Patel JR, et al. Bioorg Med Chem Lett. 2007 Feb 1;17(3):750-5. doi: 10.1016/j.bmcl.2006.10.074. Epub 2006 Oct 28. Bioorg Med Chem Lett. 2007. PMID: 17110106
Aminopiperidine indazoles as orally efficacious melanin concentrating hormone receptor-1 antagonists.
Vasudevan A, Souers AJ, Freeman JC, Verzal MK, Gao J, Mulhern MM, Wodka D, Lynch JK, Engstrom KM, Wagaw SH, Brodjian S, Dayton B, Falls DH, Bush E, Brune M, Shapiro RD, Marsh KC, Hernandez LE, Collins CA, Kym PR. Vasudevan A, et al. Among authors: engstrom km. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5293-7. doi: 10.1016/j.bmcl.2005.08.049. Epub 2005 Oct 3. Bioorg Med Chem Lett. 2005. PMID: 16203136
Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitor.
Zhao G, Souers AJ, Voorbach M, Falls HD, Droz B, Brodjian S, Lau YY, Iyengar RR, Gao J, Judd AS, Wagaw SH, Ravn MM, Engstrom KM, Lynch JK, Mulhern MM, Freeman J, Dayton BD, Wang X, Grihalde N, Fry D, Beno DW, Marsh KC, Su Z, Diaz GJ, Collins CA, Sham H, Reilly RM, Brune ME, Kym PR. Zhao G, et al. Among authors: engstrom km. J Med Chem. 2008 Feb 14;51(3):380-3. doi: 10.1021/jm7013887. Epub 2008 Jan 10. J Med Chem. 2008. PMID: 18183944
Total Synthesis of (+)-Pyrenolide D This research was supported by the National Institutes of Health, Glaxo Wellcome Inc., the Alfred P. Sloan Foundation, and the Arnold and Mabel Beckman Foundation.
Engstrom KM, Mendoza MR, Navarro-Villalobos M, Gin DY. Engstrom KM, et al. Angew Chem Int Ed Engl. 2001 Mar 16;40(6):1128-1130. doi: 10.1002/1521-3773(20010316)40:6<1128::aid-anie11280>3.0.co;2-j. Angew Chem Int Ed Engl. 2001. PMID: 11268098 No abstract available.
Metabolism of inhaled ethylbenzene in rats.
Engström KM. Engström KM. Scand J Work Environ Health. 1984 Apr;10(2):83-7. Scand J Work Environ Health. 1984. PMID: 6474105 Free article.
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