Engeli RT - Search Results

1

Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2.

Vuorinen A, Engeli RT, Leugger S, Bachmann F, Akram M, Atanasov AG, Waltenberger B, Temml V, Stuppner H, Krenn L, Ateba SB, Njamen D, Davis RA, Odermatt A, Schuster D. Vuorinen A, et al. Among authors: engeli rt. J Nat Prod. 2017 Apr 28;80(4):965-974. doi: 10.1021/acs.jnatprod.6b00950. Epub 2017 Mar 20. J Nat Prod. 2017. PMID: 28319389 Free PMC article.

2

Phenylbenzenesulfonates and -sulfonamides as 17β-hydroxysteroid dehydrogenase type 2 inhibitors: Synthesis and SAR-analysis.

Vuorinen A, Engeli RT, Leugger S, Kreutz CR, Schuster D, Odermatt A, Matuszczak B. Vuorinen A, et al. Among authors: engeli rt. Bioorg Med Chem Lett. 2017 Jul 1;27(13):2982-2985. doi: 10.1016/j.bmcl.2017.05.005. Epub 2017 May 4. Bioorg Med Chem Lett. 2017. PMID: 28506753

3

Interference of Paraben Compounds with Estrogen Metabolism by Inhibition of 17β-Hydroxysteroid Dehydrogenases.

Engeli RT, Rohrer SR, Vuorinen A, Herdlinger S, Kaserer T, Leugger S, Schuster D, Odermatt A. Engeli RT, et al. Int J Mol Sci. 2017 Sep 19;18(9):2007. doi: 10.3390/ijms18092007. Int J Mol Sci. 2017. PMID: 28925944 Free PMC article.

4

Ligand-based pharmacophore modeling and virtual screening for the discovery of novel 17β-hydroxysteroid dehydrogenase 2 inhibitors.

Vuorinen A, Engeli R, Meyer A, Bachmann F, Griesser UJ, Schuster D, Odermatt A. Vuorinen A, et al. J Med Chem. 2014 Jul 24;57(14):5995-6007. doi: 10.1021/jm5004914. Epub 2014 Jul 10. J Med Chem. 2014. PMID: 24960438 Free PMC article.

5

Biochemical analyses and molecular modeling explain the functional loss of 17β-hydroxysteroid dehydrogenase 3 mutant G133R in three Tunisian patients with 46, XY Disorders of Sex Development.

Engeli RT, Rhouma BB, Sager CP, Tsachaki M, Birk J, Fakhfakh F, Keskes L, Belguith N, Odermatt A. Engeli RT, et al. J Steroid Biochem Mol Biol. 2016 Jan;155(Pt A):147-54. doi: 10.1016/j.jsbmb.2015.10.023. Epub 2015 Nov 3. J Steroid Biochem Mol Biol. 2016. PMID: 26545797

6

Novel cases of Tunisian patients with mutations in the gene encoding 17β-hydroxysteroid dehydrogenase type 3 and a founder effect.

Ben Rhouma B, Kallabi F, Mahfoudh N, Ben Mahmoud A, Engeli RT, Kamoun H, Keskes L, Odermatt A, Belguith N. Ben Rhouma B, et al. Among authors: engeli rt. J Steroid Biochem Mol Biol. 2017 Jan;165(Pt A):86-94. doi: 10.1016/j.jsbmb.2016.03.007. Epub 2016 Mar 5. J Steroid Biochem Mol Biol. 2017. PMID: 26956191

7

Accelerated skin wound healing by selective 11β-Hydroxylase (CYP11B1) inhibitors.

Emmerich J, van Koppen CJ, Burkhart JL, Engeli RT, Hu Q, Odermatt A, Hartmann RW. Emmerich J, et al. Among authors: engeli rt. Eur J Med Chem. 2018 Jan 1;143:591-597. doi: 10.1016/j.ejmech.2017.11.018. Epub 2017 Nov 21. Eur J Med Chem. 2018. PMID: 29207342

8

Currently available murine Leydig cell lines can be applied to study early steps of steroidogenesis but not testosterone synthesis.

Engeli RT, Fürstenberger C, Kratschmar DV, Odermatt A. Engeli RT, et al. Heliyon. 2018 Feb 1;4(2):e00527. doi: 10.1016/j.heliyon.2018.e00527. eCollection 2018 Feb. Heliyon. 2018. PMID: 29560447 Free PMC article.

9

Biochemical Analysis of Four Missense Mutations in the HSD17B3 Gene Associated With 46,XY Disorders of Sex Development in Egyptian Patients.

Engeli RT, Tsachaki M, Hassan HA, Sager CP, Essawi ML, Gad YZ, Kamel AK, Mazen I, Odermatt A. Engeli RT, et al. J Sex Med. 2017 Sep;14(9):1165-1174. doi: 10.1016/j.jsxm.2017.07.006. J Sex Med. 2017. PMID: 28859874

10

Disruption of steroidogenesis: Cell models for mechanistic investigations and as screening tools.

Odermatt A, Strajhar P, Engeli RT. Odermatt A, et al. Among authors: engeli rt. J Steroid Biochem Mol Biol. 2016 Apr;158:9-21. doi: 10.1016/j.jsbmb.2016.01.009. Epub 2016 Jan 22. J Steroid Biochem Mol Biol. 2016. PMID: 26807866 Review.

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