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Contrasting patterns of Bim induction and neuroprotection in Bim-deficient mice between hippocampus and neocortex after status epilepticus.
Murphy BM, Engel T, Paucard A, Hatazaki S, Mouri G, Tanaka K, Tuffy LP, Jimenez-Mateos EM, Woods I, Dunleavy M, Bonner HP, Meller R, Simon RP, Strasser A, Prehn JH, Henshall DC. Murphy BM, et al. Among authors: engel t. Cell Death Differ. 2010 Mar;17(3):459-68. doi: 10.1038/cdd.2009.134. Epub 2009 Sep 25. Cell Death Differ. 2010. PMID: 19779495 Free PMC article.
Reduced hippocampal damage and epileptic seizures after status epilepticus in mice lacking proapoptotic Puma.
Engel T, Murphy BM, Hatazaki S, Jimenez-Mateos EM, Concannon CG, Woods I, Prehn JH, Henshall DC. Engel T, et al. FASEB J. 2010 Mar;24(3):853-61. doi: 10.1096/fj.09-145870. Epub 2009 Nov 4. FASEB J. 2010. PMID: 19890018 Free PMC article.
These are the first data showing genetic deletion of a proapoptotic protein acting acutely to influence neuronal death subsequently alters the phenotype of epilepsy in the long-term, supporting the concept that apoptotic pathway activation is a trigger of epileptogenesis.-Enge …
These are the first data showing genetic deletion of a proapoptotic protein acting acutely to influence neuronal death subsequently alters t …
Reduced mature microRNA levels in association with dicer loss in human temporal lobe epilepsy with hippocampal sclerosis.
McKiernan RC, Jimenez-Mateos EM, Bray I, Engel T, Brennan GP, Sano T, Michalak Z, Moran C, Delanty N, Farrell M, O'Brien D, Meller R, Simon RP, Stallings RL, Henshall DC. McKiernan RC, et al. Among authors: engel t. PLoS One. 2012;7(5):e35921. doi: 10.1371/journal.pone.0035921. Epub 2012 May 15. PLoS One. 2012. PMID: 22615744 Free PMC article.
Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects.
Jimenez-Mateos EM, Engel T, Merino-Serrais P, McKiernan RC, Tanaka K, Mouri G, Sano T, O'Tuathaigh C, Waddington JL, Prenter S, Delanty N, Farrell MA, O'Brien DF, Conroy RM, Stallings RL, DeFelipe J, Henshall DC. Jimenez-Mateos EM, et al. Among authors: engel t. Nat Med. 2012 Jul;18(7):1087-94. doi: 10.1038/nm.2834. Nat Med. 2012. PMID: 22683779 Free PMC article.
Looking for novel functions of tau.
Avila J, de Barreda EG, Fuster-Matanzo A, Simón D, Llorens-Martín M, Engel T, Lucas JJ, Díaz-Hernández M, Hernández F. Avila J, et al. Among authors: engel t. Biochem Soc Trans. 2012 Aug;40(4):653-5. doi: 10.1042/BST20120006. Biochem Soc Trans. 2012. PMID: 22817710 Review.
453 results