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Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium.
Jardé T, Chan WH, Rossello FJ, Kaur Kahlon T, Theocharous M, Kurian Arackal T, Flores T, Giraud M, Richards E, Chan E, Kerr G, Engel RM, Prasko M, Donoghue JF, Abe SI, Phesse TJ, Nefzger CM, McMurrick PJ, Powell DR, Daly RJ, Polo JM, Abud HE. Jardé T, et al. Among authors: engel rm. Cell Stem Cell. 2020 Oct 1;27(4):646-662.e7. doi: 10.1016/j.stem.2020.06.021. Epub 2020 Jul 20. Cell Stem Cell. 2020. PMID: 32693086 Free article.
Clostridioides difficile infection damages colonic stem cells via TcdB, impairing epithelial repair and recovery from disease.
Mileto SJ, Jardé T, Childress KO, Jensen JL, Rogers AP, Kerr G, Hutton ML, Sheedlo MJ, Bloch SC, Shupe JA, Horvay K, Flores T, Engel R, Wilkins S, McMurrick PJ, Lacy DB, Abud HE, Lyras D. Mileto SJ, et al. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):8064-8073. doi: 10.1073/pnas.1915255117. Epub 2020 Mar 20. Proc Natl Acad Sci U S A. 2020. PMID: 32198200 Free PMC article.
Modeling colorectal cancer: A bio-resource of 50 patient-derived organoid lines.
Engel RM, Jardé T, Oliva K, Kerr G, Chan WH, Hlavca S, Nickless D, Archer SK, Yap R, Ranchod P, Bell S, Niap A, Koulis C, Chong A, Wilkins S, Dale TC, Hollins AJ, McMurrick PJ, Abud HE. Engel RM, et al. J Gastroenterol Hepatol. 2022 May;37(5):898-907. doi: 10.1111/jgh.15818. Epub 2022 Mar 10. J Gastroenterol Hepatol. 2022. PMID: 35244298 Free PMC article.
Intestinal stem cell aging signature reveals a reprogramming strategy to enhance regenerative potential.
Nefzger CM, Jardé T, Srivastava A, Schroeder J, Rossello FJ, Horvay K, Prasko M, Paynter JM, Chen J, Weng CF, Sun YBY, Liu X, Chan E, Deshpande N, Chen X, Li YJ, Pflueger J, Engel RM, Knaupp AS, Tsyganov K, Nilsson SK, Lister R, Rackham OJL, Abud HE, Polo JM. Nefzger CM, et al. Among authors: engel rm. NPJ Regen Med. 2022 Jun 16;7(1):31. doi: 10.1038/s41536-022-00226-7. NPJ Regen Med. 2022. PMID: 35710627 Free PMC article.
88 results