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FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism.
Sakaguchi M, Cai W, Wang CH, Cederquist CT, Damasio M, Homan EP, Batista T, Ramirez AK, Gupta MK, Steger M, Wewer Albrechtsen NJ, Singh SK, Araki E, Mann M, Enerbäck S, Kahn CR. Sakaguchi M, et al. Among authors: enerback s. Nat Commun. 2019 Apr 5;10(1):1582. doi: 10.1038/s41467-019-09418-0. Nat Commun. 2019. PMID: 30952843 Free PMC article.
FOXK1 and FOXK2 regulate aerobic glycolysis.
Sukonina V, Ma H, Zhang W, Bartesaghi S, Subhash S, Heglind M, Foyn H, Betz MJ, Nilsson D, Lidell ME, Naumann J, Haufs-Brusberg S, Palmgren H, Mondal T, Beg M, Jedrychowski MP, Taskén K, Pfeifer A, Peng XR, Kanduri C, Enerbäck S. Sukonina V, et al. Among authors: enerback s. Nature. 2019 Feb;566(7743):279-283. doi: 10.1038/s41586-019-0900-5. Epub 2019 Jan 30. Nature. 2019. PMID: 30700909
The adipocyte-expressed forkhead transcription factor Foxc2 regulates metabolism through altered mitochondrial function.
Lidell ME, Seifert EL, Westergren R, Heglind M, Gowing A, Sukonina V, Arani Z, Itkonen P, Wallin S, Westberg F, Fernandez-Rodriguez J, Laakso M, Nilsson T, Peng XR, Harper ME, Enerbäck S. Lidell ME, et al. Among authors: enerback s. Diabetes. 2011 Feb;60(2):427-35. doi: 10.2337/db10-0409. Diabetes. 2011. PMID: 21270254 Free PMC article.
The Gq signalling pathway inhibits brown and beige adipose tissue.
Klepac K, Kilić A, Gnad T, Brown LM, Herrmann B, Wilderman A, Balkow A, Glöde A, Simon K, Lidell ME, Betz MJ, Enerbäck S, Wess J, Freichel M, Blüher M, König G, Kostenis E, Insel PA, Pfeifer A. Klepac K, et al. Among authors: enerback s. Nat Commun. 2016 Mar 9;7:10895. doi: 10.1038/ncomms10895. Nat Commun. 2016. PMID: 26955961 Free PMC article.
Evidence for two types of brown adipose tissue in humans.
Lidell ME, Betz MJ, Dahlqvist Leinhard O, Heglind M, Elander L, Slawik M, Mussack T, Nilsson D, Romu T, Nuutila P, Virtanen KA, Beuschlein F, Persson A, Borga M, Enerbäck S. Lidell ME, et al. Among authors: enerback s. Nat Med. 2013 May;19(5):631-4. doi: 10.1038/nm.3017. Epub 2013 Apr 21. Nat Med. 2013. PMID: 23603813
Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors.
Gnad T, Scheibler S, von Kügelgen I, Scheele C, Kilić A, Glöde A, Hoffmann LS, Reverte-Salisa L, Horn P, Mutlu S, El-Tayeb A, Kranz M, Deuther-Conrad W, Brust P, Lidell ME, Betz MJ, Enerbäck S, Schrader J, Yegutkin GG, Müller CE, Pfeifer A. Gnad T, et al. Among authors: enerback s. Nature. 2014 Dec 18;516(7531):395-9. doi: 10.1038/nature13816. Epub 2014 Oct 15. Nature. 2014. PMID: 25317558
Foxc2 is essential for podocyte function.
Nilsson D, Heglind M, Arani Z, Enerbäck S. Nilsson D, et al. Among authors: enerback s. Physiol Rep. 2019 May;7(9):e14083. doi: 10.14814/phy2.14083. Physiol Rep. 2019. PMID: 31062503 Free PMC article.
141 results