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Metformin suppresses intestinal polyp growth in ApcMin/+ mice.
Tomimoto A, Endo H, Sugiyama M, Fujisawa T, Hosono K, Takahashi H, Nakajima N, Nagashima Y, Wada K, Nakagama H, Nakajima A. Tomimoto A, et al. Among authors: endo h. Cancer Sci. 2008 Nov;99(11):2136-41. doi: 10.1111/j.1349-7006.2008.00933.x. Epub 2008 Sep 18. Cancer Sci. 2008. PMID: 18803638 Free article.
Inhibition of peroxisome proliferator-activated receptor gamma activity suppresses pancreatic cancer cell motility.
Nakajima A, Tomimoto A, Fujita K, Sugiyama M, Takahashi H, Ikeda I, Hosono K, Endo H, Yoneda K, Iida H, Inamori M, Kubota K, Saito S, Nakajima N, Wada K, Nagashima Y, Nakagama H. Nakajima A, et al. Among authors: endo h. Cancer Sci. 2008 Oct;99(10):1892-900. doi: 10.1111/j.1349-7006.2008.00904.x. Cancer Sci. 2008. PMID: 19016747 Free article.
Inhibition of peroxisome proliferator-activated receptor gamma promotes tumorigenesis through activation of the beta-catenin / T cell factor (TCF) pathway in the mouse intestine.
Fujisawa T, Sugiyama M, Tomimoto A, Wada K, Endo H, Takahashi H, Yoneda K, Yoneda M, Inamori M, Saito S, Terauchi Y, Kadowaki T, Tsuchiya N, Nakagama H, Nakajima A. Fujisawa T, et al. Among authors: endo h. J Pharmacol Sci. 2008 Dec;108(4):535-44. doi: 10.1254/jphs.08193fp. Epub 2008 Dec 10. J Pharmacol Sci. 2008. PMID: 19075513 Free article.
Metformin suppresses colorectal aberrant crypt foci in a short-term clinical trial.
Hosono K, Endo H, Takahashi H, Sugiyama M, Sakai E, Uchiyama T, Suzuki K, Iida H, Sakamoto Y, Yoneda K, Koide T, Tokoro C, Abe Y, Inamori M, Nakagama H, Nakajima A. Hosono K, et al. Among authors: endo h. Cancer Prev Res (Phila). 2010 Sep;3(9):1077-83. doi: 10.1158/1940-6207.CAPR-10-0186. Epub 2010 Sep 1. Cancer Prev Res (Phila). 2010. PMID: 20810669 Clinical Trial.
Leptin receptor is involved in STAT3 activation in human colorectal adenoma.
Uchiyama T, Takahashi H, Sugiyama M, Sakai E, Endo H, Hosono K, Yoneda K, Yoneda M, Inamori M, Nagashima Y, Inayama Y, Wada K, Nakajima A. Uchiyama T, et al. Among authors: endo h. Cancer Sci. 2011 Feb;102(2):367-72. doi: 10.1111/j.1349-7006.2010.01803.x. Epub 2010 Dec 19. Cancer Sci. 2011. PMID: 21166956 Free article.
Metformin efficacy and safety for colorectal polyps: a double-blind randomized controlled trial.
Higurashi T, Takahashi H, Endo H, Hosono K, Yamada E, Ohkubo H, Sakai E, Uchiyama T, Hata Y, Fujisawa N, Uchiyama S, Ezuka A, Nagase H, Kessoku T, Matsuhashi N, Yamanaka S, Inayama Y, Morita S, Nakajima A. Higurashi T, et al. Among authors: endo h. BMC Cancer. 2012 Mar 26;12:118. doi: 10.1186/1471-2407-12-118. BMC Cancer. 2012. PMID: 22443173 Free PMC article. Clinical Trial.
Life style-related diseases of the digestive system: colorectal cancer as a life style-related disease: from carcinogenesis to medical treatment.
Takahashi H, Yoneda K, Tomimoto A, Endo H, Fujisawa T, Iida H, Mawatari H, Nozaki Y, Ikeda T, Akiyama T, Yoneda M, Inamori M, Abe Y, Saito S, Nakajima A, Nakagama H. Takahashi H, et al. Among authors: endo h. J Pharmacol Sci. 2007 Oct;105(2):129-32. doi: 10.1254/jphs.fm0070022. Epub 2007 Oct 6. J Pharmacol Sci. 2007. PMID: 17928742 Free article. Review.
2,339 results