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Year Number of Results
2007 2
2008 3
2009 2
2010 1
2011 4
2012 3
2013 2
2014 5
2015 1
2016 1
2017 2
2018 3
2019 3
2021 1
2023 1
2024 1

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33 results

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Oncogenic KEAP1 mutations activate TRAF2-NFκB signaling to prevent apoptosis in lung cancer cells.
Deen AJ, Adinolfi S, Härkönen J, Patinen T, Liu X, Laitinen T, Takabe P, Kainulainen K, Pasonen-Seppänen S, Gawriyski LM, Arasu UT, Selvarajan I, Mäkinen P, Laitinen H, Kansanen E, Kaikkonen MU, Poso A, Varjosalo M, Levonen AL. Deen AJ, et al. Among authors: kansanen e. Redox Biol. 2024 Feb;69:103031. doi: 10.1016/j.redox.2024.103031. Epub 2024 Jan 4. Redox Biol. 2024. PMID: 38184997 Free PMC article.
The KEAP1-NRF2 pathway: Targets for therapy and role in cancer.
Adinolfi S, Patinen T, Jawahar Deen A, Pitkänen S, Härkönen J, Kansanen E, Küblbeck J, Levonen AL. Adinolfi S, et al. Among authors: kansanen e. Redox Biol. 2023 Jul;63:102726. doi: 10.1016/j.redox.2023.102726. Epub 2023 Apr 29. Redox Biol. 2023. PMID: 37146513 Free PMC article. Review.
NRF2 is a key regulator of endothelial microRNA expression under proatherogenic stimuli.
Linna-Kuosmanen S, Tomas Bosch V, Moreau PR, Bouvy-Liivrand M, Niskanen H, Kansanen E, Kivelä A, Hartikainen J, Hippeläinen M, Kokki H, Tavi P, Levonen AL, Kaikkonen MU. Linna-Kuosmanen S, et al. Among authors: kansanen e. Cardiovasc Res. 2021 Apr 23;117(5):1339-1357. doi: 10.1093/cvr/cvaa219. Cardiovasc Res. 2021. PMID: 32683448 Free PMC article.
In Vitro and In Vivo Pipeline for Validation of Disease-Modifying Effects of Systems Biology-Derived Network Treatments for Traumatic Brain Injury-Lessons Learned.
Lipponen A, Natunen T, Hujo M, Ciszek R, Hämäläinen E, Tohka J, Hiltunen M, Paananen J, Poulsen D, Kansanen E, Ekolle Ndode-Ekane X, Levonen AL, Pitkänen A. Lipponen A, et al. Among authors: kansanen e. Int J Mol Sci. 2019 Oct 29;20(21):5395. doi: 10.3390/ijms20215395. Int J Mol Sci. 2019. PMID: 31671916 Free PMC article.
Nuclear factor E2-related factor 2 deficiency impairs atherosclerotic lesion development but promotes features of plaque instability in hypercholesterolaemic mice.
Ruotsalainen AK, Lappalainen JP, Heiskanen E, Merentie M, Sihvola V, Näpänkangas J, Lottonen-Raikaslehto L, Kansanen E, Adinolfi S, Kaarniranta K, Ylä-Herttuala S, Jauhiainen M, Pirinen E, Levonen AL. Ruotsalainen AK, et al. Among authors: kansanen e. Cardiovasc Res. 2019 Jan 1;115(1):243-254. doi: 10.1093/cvr/cvy143. Cardiovasc Res. 2019. PMID: 29917052
NRF2 regulates endothelial glycolysis and proliferation with miR-93 and mediates the effects of oxidized phospholipids on endothelial activation.
Kuosmanen SM, Kansanen E, Kaikkonen MU, Sihvola V, Pulkkinen K, Jyrkkänen HK, Tuoresmäki P, Hartikainen J, Hippeläinen M, Kokki H, Tavi P, Heikkinen S, Levonen AL. Kuosmanen SM, et al. Among authors: kansanen e. Nucleic Acids Res. 2018 Feb 16;46(3):1124-1138. doi: 10.1093/nar/gkx1155. Nucleic Acids Res. 2018. PMID: 29161413 Free PMC article.
33 results