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Scientific and regulatory evaluation of mechanistic in silico drug and disease models in drug development: Building model credibility.
Musuamba FT, Skottheim Rusten I, Lesage R, Russo G, Bursi R, Emili L, Wangorsch G, Manolis E, Karlsson KE, Kulesza A, Courcelles E, Boissel JP, Rousseau CF, Voisin EM, Alessandrello R, Curado N, Dall'ara E, Rodriguez B, Pappalardo F, Geris L. Musuamba FT, et al. Among authors: emili l. CPT Pharmacometrics Syst Pharmacol. 2021 Aug;10(8):804-825. doi: 10.1002/psp4.12669. Epub 2021 Jul 13. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 34102034 Free PMC article.
Possible Contexts of Use for In Silico Trials Methodologies: A Consensus-Based Review.
Viceconti M, Emili L, Afshari P, Courcelles E, Curreli C, Famaey N, Geris L, Horner M, Jori MC, Kulesza A, Loewe A, Neidlin M, Reiterer M, Rousseau CF, Russo G, Sonntag SJ, Voisin EM, Pappalardo F. Viceconti M, et al. Among authors: emili l. IEEE J Biomed Health Inform. 2021 Oct;25(10):3977-3982. doi: 10.1109/JBHI.2021.3090469. Epub 2021 Oct 5. IEEE J Biomed Health Inform. 2021. PMID: 34161248 Free article. Review.