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Mobilization of innate and adaptive antitumor immune responses by the RNP-targeting antibody ATRC-101.
Scholz A, DeFalco J, Leung Y, Aydin IT, Czupalla CJ, Cao W, Santos D, Vad N, Lippow SM, Baia G, Harbell M, Sapugay J, Zhang D, Wu DC, Wechsler E, Ye AZ, Wu JW, Peng X, Vivian J, Kaplan H, Collins R, Nguyen N, Whidden M, Kim D, Millward C, Benjamin J, Greenberg NM, Serafini TA, Emerling DE, Steinman L, Robinson WH, Manning-Bog A. Scholz A, et al. Among authors: emerling de. Proc Natl Acad Sci U S A. 2022 May 10;119(19):e2123483119. doi: 10.1073/pnas.2123483119. Epub 2022 May 4. Proc Natl Acad Sci U S A. 2022. PMID: 35507878 Free PMC article.
TRPM8 biology and medicinal chemistry.
DeFalco J, Duncton MA, Emerling D. DeFalco J, et al. Curr Top Med Chem. 2011;11(17):2237-52. doi: 10.2174/156802611796904933. Curr Top Med Chem. 2011. PMID: 21671871 Review.
Non-progressing cancer patients have persistent B cell responses expressing shared antibody paratopes that target public tumor antigens.
DeFalco J, Harbell M, Manning-Bog A, Baia G, Scholz A, Millare B, Sumi M, Zhang D, Chu F, Dowd C, Zuno-Mitchell P, Kim D, Leung Y, Jiang S, Tang X, Williamson KS, Chen X, Carroll SM, Espiritu Santo G, Haaser N, Nguyen N, Giladi E, Minor D, Tan YC, Sokolove JB, Steinman L, Serafini TA, Cavet G, Greenberg NM, Glanville J, Volkmuth W, Emerling DE, Robinson WH. DeFalco J, et al. Among authors: emerling de. Clin Immunol. 2018 Feb;187:37-45. doi: 10.1016/j.clim.2017.10.002. Epub 2017 Oct 12. Clin Immunol. 2018. PMID: 29031828 Free article.
Longitudinal analysis of acute and convalescent B cell responses in a human primary dengue serotype 2 infection model.
Nivarthi UK, Tu HA, Delacruz MJ, Swanstrom J, Patel B, Durbin AP, Whitehead SS, Pierce KK, Kirkpatrick BD, Baric RS, Nguyen N, Emerling DE, de Silva AM, Diehl SA. Nivarthi UK, et al. Among authors: emerling de. EBioMedicine. 2019 Mar;41:465-478. doi: 10.1016/j.ebiom.2019.02.060. Epub 2019 Mar 8. EBioMedicine. 2019. PMID: 30857944 Free PMC article.
A candidate antibody drug for prevention of malaria.
Williams KL, Guerrero S, Flores-Garcia Y, Kim D, Williamson KS, Siska C, Smidt P, Jepson SZ, Li K, Dennison SM, Mathis-Torres S, Chen X, Wille-Reece U, MacGill RS, Walker M, Jongert E, King CR, Ockenhouse C, Glanville J, Moon JE, Regules JA, Tan YC, Cavet G, Lippow SM, Robinson WH, Dutta S, Tomaras GD, Zavala F, Ketchem RR, Emerling DE. Williams KL, et al. Among authors: emerling de. Nat Med. 2024 Jan;30(1):117-129. doi: 10.1038/s41591-023-02659-z. Epub 2024 Jan 2. Nat Med. 2024. PMID: 38167935 Free PMC article.
Identification and characterization of novel TRPV4 modulators.
Vincent F, Acevedo A, Nguyen MT, Dourado M, DeFalco J, Gustafson A, Spiro P, Emerling DE, Kelly MG, Duncton MA. Vincent F, et al. Among authors: emerling de. Biochem Biophys Res Commun. 2009 Nov 20;389(3):490-4. doi: 10.1016/j.bbrc.2009.09.007. Epub 2009 Sep 6. Biochem Biophys Res Commun. 2009. PMID: 19737537
27 results