Puromycin reveals a distinct conformation of neuronal ribosomes.
Anadolu MN, Sun J, Li JT, Graber TE, Ortega J, Sossin WS.
Anadolu MN, et al.
Proc Natl Acad Sci U S A. 2024 Feb 13;121(7):e2306993121. doi: 10.1073/pnas.2306993121. Epub 2024 Feb 5.
Proc Natl Acad Sci U S A. 2024.
PMID: 38315848
It was postulated that blocking the translocation of the ribosome with emetine could retain the puromycylated peptide on the ribosome, but evidence against this has recently been published [Hobson et al., Elife 9, e60048 (2020); and Enam et al., Elife 9, e60303 (2020)]. In …
It was postulated that blocking the translocation of the ribosome with emetine could retain the puromycylated peptide on the ribosome, but …