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Page 1
Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis.
Sveidahl Johansen O, Ma T, Hansen JB, Markussen LK, Schreiber R, Reverte-Salisa L, Dong H, Christensen DP, Sun W, Gnad T, Karavaeva I, Nielsen TS, Kooijman S, Cero C, Dmytriyeva O, Shen Y, Razzoli M, O'Brien SL, Kuipers EN, Nielsen CH, Orchard W, Willemsen N, Jespersen NZ, Lundh M, Sustarsic EG, Hallgren CM, Frost M, McGonigle S, Isidor MS, Broholm C, Pedersen O, Hansen JB, Grarup N, Hansen T, Kjær A, Granneman JG, Babu MM, Calebiro D, Nielsen S, Rydén M, Soccio R, Rensen PCN, Treebak JT, Schwartz TW, Emanuelli B, Bartolomucci A, Pfeifer A, Zechner R, Scheele C, Mandrup S, Gerhart-Hines Z. Sveidahl Johansen O, et al. Among authors: emanuelli b. Cell. 2021 Jun 24;184(13):3502-3518.e33. doi: 10.1016/j.cell.2021.04.037. Epub 2021 May 27. Cell. 2021. PMID: 34048700 Free PMC article.
Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis.
Sustarsic EG, Ma T, Lynes MD, Larsen M, Karavaeva I, Havelund JF, Nielsen CH, Jedrychowski MP, Moreno-Torres M, Lundh M, Plucinska K, Jespersen NZ, Grevengoed TJ, Kramar B, Peics J, Hansen JB, Shamsi F, Forss I, Neess D, Keipert S, Wang J, Stohlmann K, Brandslund I, Christensen C, Jørgensen ME, Linneberg A, Pedersen O, Kiebish MA, Qvortrup K, Han X, Pedersen BK, Jastroch M, Mandrup S, Kjær A, Gygi SP, Hansen T, Gillum MP, Grarup N, Emanuelli B, Nielsen S, Scheele C, Tseng YH, Færgeman NJ, Gerhart-Hines Z. Sustarsic EG, et al. Among authors: emanuelli b. Cell Metab. 2018 Jul 3;28(1):159-174.e11. doi: 10.1016/j.cmet.2018.05.003. Epub 2018 May 31. Cell Metab. 2018. PMID: 29861389 Free PMC article.
Afadin is a scaffold protein repressing insulin action via HDAC6 in adipose tissue.
Lundh M, Petersen PS, Isidor MS, Kazoka-Sørensen DN, Plucińska K, Shamsi F, Ørskov C, Tozzi M, Brown EL, Andersen E, Ma T, Müller U, Barrès R, Kristiansen VB, Gerhart-Hines Z, Tseng YH, Emanuelli B. Lundh M, et al. Among authors: emanuelli b. EMBO Rep. 2019 Aug;20(8):e48216. doi: 10.15252/embr.201948216. Epub 2019 Jul 2. EMBO Rep. 2019. PMID: 31264358 Free PMC article.
Pyruvate kinase M2 represses thermogenic gene expression in brown adipocytes.
Isidor MS, Winther S, Markussen LK, Basse AL, Quistorff B, Nedergaard J, Emanuelli B, Hansen JB. Isidor MS, et al. Among authors: emanuelli b. FEBS Lett. 2020 Apr;594(7):1218-1225. doi: 10.1002/1873-3468.13716. Epub 2019 Dec 20. FEBS Lett. 2020. PMID: 31823361 Free article.
Fasting- and ghrelin-induced food intake is regulated by NAMPT in the hypothalamus.
de Guia RM, Hassing AS, Skov LJ, Ratner C, Plucińska K, Madsen S, Diep TA, Dela Cruz GV, Trammell SAJ, Sustarsic EG, Emanuelli B, Gillum MP, Gerhart-Hines Z, Holst B, Treebak JT. de Guia RM, et al. Among authors: emanuelli b. Acta Physiol (Oxf). 2020 Apr;228(4):e13437. doi: 10.1111/apha.13437. Epub 2020 Jan 14. Acta Physiol (Oxf). 2020. PMID: 31900990
FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis.
Shamsi F, Xue R, Huang TL, Lundh M, Liu Y, Leiria LO, Lynes MD, Kempf E, Wang CH, Sugimoto S, Nigro P, Landgraf K, Schulz T, Li Y, Emanuelli B, Kothakota S, Williams LT, Jessen N, Pedersen SB, Böttcher Y, Blüher M, Körner A, Goodyear LJ, Mohammadi M, Kahn CR, Tseng YH. Shamsi F, et al. Among authors: emanuelli b. Nat Commun. 2020 Mar 17;11(1):1421. doi: 10.1038/s41467-020-15055-9. Nat Commun. 2020. PMID: 32184391 Free PMC article.
Human thermogenic adipocyte regulation by the long noncoding RNA LINC00473.
Tran KV, Brown EL, DeSouza T, Jespersen NZ, Nandrup-Bus C, Yang Q, Yang Z, Desai A, Min SY, Rojas-Rodriguez R, Lundh M, Feizi A, Willenbrock H, Larsen TJ, Severinsen MCK, Malka K, Mozzicato AM, Deshmukh AS, Emanuelli B, Pedersen BK, Fitzgibbons T, Scheele C, Corvera S, Nielsen S. Tran KV, et al. Among authors: emanuelli b. Nat Metab. 2020 May;2(5):397-412. doi: 10.1038/s42255-020-0205-x. Epub 2020 May 21. Nat Metab. 2020. PMID: 32440655 Free PMC article.
CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice.
Wang CH, Lundh M, Fu A, Kriszt R, Huang TL, Lynes MD, Leiria LO, Shamsi F, Darcy J, Greenwood BP, Narain NR, Tolstikov V, Smith KL, Emanuelli B, Chang YT, Hagen S, Danial NN, Kiebish MA, Tseng YH. Wang CH, et al. Among authors: emanuelli b. Sci Transl Med. 2020 Aug 26;12(558):eaaz8664. doi: 10.1126/scitranslmed.aaz8664. Sci Transl Med. 2020. PMID: 32848096 Free PMC article.
46 results