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Multi-ancestry Mendelian randomization of omics traits revealing drug targets of COVID-19 severity.
Zheng J, Zhang Y, Zhao H, Liu Y, Baird D, Karim MA, Ghoussaini M, Schwartzentruber J, Dunham I, Elsworth B, Roberts K, Compton H, Miller-Molloy F, Liu X, Wang L, Zhang H, Smith GD, Gaunt TR. Zheng J, et al. Among authors: elsworth b. EBioMedicine. 2022 Jul;81:104112. doi: 10.1016/j.ebiom.2022.104112. Epub 2022 Jun 27. EBioMedicine. 2022. PMID: 35772218 Free PMC article.
LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis.
Zheng J, Erzurumluoglu AM, Elsworth BL, Kemp JP, Howe L, Haycock PC, Hemani G, Tansey K, Laurin C; Early Genetics and Lifecourse Epidemiology (EAGLE) Eczema Consortium; Pourcain BS, Warrington NM, Finucane HK, Price AL, Bulik-Sullivan BK, Anttila V, Paternoster L, Gaunt TR, Evans DM, Neale BM. Zheng J, et al. Bioinformatics. 2017 Jan 15;33(2):272-279. doi: 10.1093/bioinformatics/btw613. Epub 2016 Sep 22. Bioinformatics. 2017. PMID: 27663502 Free PMC article.
MELODI: Mining Enriched Literature Objects to Derive Intermediates.
Elsworth B, Dawe K, Vincent EE, Langdon R, Lynch BM, Martin RM, Relton C, Higgins JPT, Gaunt TR. Elsworth B, et al. Int J Epidemiol. 2018 Jan 12;47(2):369-79. doi: 10.1093/ije/dyx251. Online ahead of print. Int J Epidemiol. 2018. PMID: 29342271 Free PMC article.
The MR-Base platform supports systematic causal inference across the human phenome.
Hemani G, Zheng J, Elsworth B, Wade KH, Haberland V, Baird D, Laurin C, Burgess S, Bowden J, Langdon R, Tan VY, Yarmolinsky J, Shihab HA, Timpson NJ, Evans DM, Relton C, Martin RM, Davey Smith G, Gaunt TR, Haycock PC. Hemani G, et al. Among authors: elsworth b. Elife. 2018 May 30;7:e34408. doi: 10.7554/eLife.34408. Elife. 2018. PMID: 29846171 Free PMC article.
Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and Fractures.
Zheng J, Maerz W, Gergei I, Kleber M, Drechsler C, Wanner C, Brandenburg V, Reppe S, Gautvik KM, Medina-Gomez C, Shevroja E, Gilly A, Park YC, Dedoussis G, Zeggini E, Lorentzon M, Henning P, Lerner UH, Nilsson KH, Movérare-Skrtic S, Baird D, Elsworth B, Falk L, Groom A, Capellini TD, Grundberg E, Nethander M, Ohlsson C, Davey Smith G, Tobias JH. Zheng J, et al. Among authors: elsworth b. J Bone Miner Res. 2019 Oct;34(10):1824-1836. doi: 10.1002/jbmr.3803. Epub 2019 Aug 2. J Bone Miner Res. 2019. PMID: 31170332 Free PMC article.
Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases.
Zheng J, Haberland V, Baird D, Walker V, Haycock PC, Hurle MR, Gutteridge A, Erola P, Liu Y, Luo S, Robinson J, Richardson TG, Staley JR, Elsworth B, Burgess S, Sun BB, Danesh J, Runz H, Maranville JC, Martin HM, Yarmolinsky J, Laurin C, Holmes MV, Liu JZ, Estrada K, Santos R, McCarthy L, Waterworth D, Nelson MR, Smith GD, Butterworth AS, Hemani G, Scott RA, Gaunt TR. Zheng J, et al. Among authors: elsworth b. Nat Genet. 2020 Oct;52(10):1122-1131. doi: 10.1038/s41588-020-0682-6. Epub 2020 Sep 7. Nat Genet. 2020. PMID: 32895551 Free PMC article.
EpiGraphDB: a database and data mining platform for health data science.
Liu Y, Elsworth B, Erola P, Haberland V, Hemani G, Lyon M, Zheng J, Lloyd O, Vabistsevits M, Gaunt TR. Liu Y, et al. Among authors: elsworth b. Bioinformatics. 2021 Jun 9;37(9):1304-1311. doi: 10.1093/bioinformatics/btaa961. Bioinformatics. 2021. PMID: 33165574 Free PMC article.
53 results