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Fibroblast Activation Protein Triggers Release of Drug Payload from Non-internalizing Small Molecule Drug Conjugates in Solid Tumors.
Zana A, Galbiati A, Gilardoni E, Bocci M, Millul J, Sturm T, Stucchi R, Elsayed A, Nadal L, Cirillo M, Roll W, Stegger L, Asmus I, Backhaus P, Schäfers M, Neri D, Cazzamalli S. Zana A, et al. Among authors: elsayed a. Clin Cancer Res. 2022 Dec 15;28(24):5440-5454. doi: 10.1158/1078-0432.CCR-22-1788. Clin Cancer Res. 2022. PMID: 36215129
A DNA-Encoded Chemical Library Based on Peptide Macrocycles.
Onda Y, Bassi G, Elsayed A, Ulrich F, Oehler S, Plais L, Scheuermann J, Neri D. Onda Y, et al. Among authors: elsayed a. Chemistry. 2021 Apr 26;27(24):7160-7167. doi: 10.1002/chem.202005423. Epub 2021 Mar 18. Chemistry. 2021. PMID: 33586277
An ultra-high-affinity small organic ligand of fibroblast activation protein for tumor-targeting applications.
Millul J, Bassi G, Mock J, Elsayed A, Pellegrino C, Zana A, Dakhel Plaza S, Nadal L, Gloger A, Schmidt E, Biancofiore I, Donckele EJ, Samain F, Neri D, Cazzamalli S. Millul J, et al. Among authors: elsayed a. Proc Natl Acad Sci U S A. 2021 Apr 20;118(16):e2101852118. doi: 10.1073/pnas.2101852118. Proc Natl Acad Sci U S A. 2021. PMID: 33850024 Free PMC article.
Generation and in vivo validation of an IL-12 fusion protein based on a novel anti-human FAP monoclonal antibody.
Nadal L, Peissert F, Elsayed A, Weiss T, Look T, Weller M, Piro G, Carbone C, Tortora G, Matasci M, Favalli N, Corbellari R, Di Nitto C, Prodi E, Libbra C, Galeazzi S, Carotenuto C, Halin C, Puca E, Neri D, De Luca R. Nadal L, et al. Among authors: elsayed a. J Immunother Cancer. 2022 Sep;10(9):e005282. doi: 10.1136/jitc-2022-005282. J Immunother Cancer. 2022. PMID: 36104101 Free PMC article.
A DNA-encoded chemical library based on chiral 4-amino-proline enables stereospecific isozyme-selective protein recognition.
Oehler S, Lucaroni L, Migliorini F, Elsayed A, Prati L, Puglioli S, Matasci M, Schira K, Scheuermann J, Yudin D, Jia M, Ban N, Bushnell D, Kornberg R, Cazzamalli S, Neri D, Favalli N, Bassi G. Oehler S, et al. Among authors: elsayed a. Nat Chem. 2023 Oct;15(10):1431-1443. doi: 10.1038/s41557-023-01257-3. Epub 2023 Jul 3. Nat Chem. 2023. PMID: 37400597
1,168 results