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Na+ controls hypoxic signalling by the mitochondrial respiratory chain.
Hernansanz-Agustín P, Choya-Foces C, Carregal-Romero S, Ramos E, Oliva T, Villa-Piña T, Moreno L, Izquierdo-Álvarez A, Cabrera-García JD, Cortés A, Lechuga-Vieco AV, Jadiya P, Navarro E, Parada E, Palomino-Antolín A, Tello D, Acín-Pérez R, Rodríguez-Aguilera JC, Navas P, Cogolludo Á, López-Montero I, Martínez-Del-Pozo Á, Egea J, López MG, Elrod JW, Ruíz-Cabello J, Bogdanova A, Enríquez JA, Martínez-Ruiz A. Hernansanz-Agustín P, et al. Among authors: elrod jw. Nature. 2020 Oct;586(7828):287-291. doi: 10.1038/s41586-020-2551-y. Epub 2020 Jul 29. Nature. 2020. PMID: 32728214 Free PMC article.
The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability.
Luongo TS, Lambert JP, Gross P, Nwokedi M, Lombardi AA, Shanmughapriya S, Carpenter AC, Kolmetzky D, Gao E, van Berlo JH, Tsai EJ, Molkentin JD, Chen X, Madesh M, Houser SR, Elrod JW. Luongo TS, et al. Among authors: elrod jw. Nature. 2017 May 4;545(7652):93-97. doi: 10.1038/nature22082. Epub 2017 Apr 26. Nature. 2017. PMID: 28445457 Free PMC article.
Is the Failing Heart Starved of Mitochondrial Calcium?
Garbincius JF, Elrod JW. Garbincius JF, et al. Among authors: elrod jw. Circ Res. 2021 Apr 16;128(8):1205-1207. doi: 10.1161/CIRCRESAHA.121.319030. Epub 2021 Apr 15. Circ Res. 2021. PMID: 33856917 Free PMC article. No abstract available.
108 results