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Mitochondrial Dysfunction, Through Impaired Autophagy, Leads to Endoplasmic Reticulum Stress, Deregulated Lipid Metabolism, and Pancreatitis in Animal Models.
Biczo G, Vegh ET, Shalbueva N, Mareninova OA, Elperin J, Lotshaw E, Gretler S, Lugea A, Malla SR, Dawson D, Ruchala P, Whitelegge J, French SW, Wen L, Husain SZ, Gorelick FS, Hegyi P, Rakonczay Z Jr, Gukovsky I, Gukovskaya AS. Biczo G, et al. Among authors: elperin j. Gastroenterology. 2018 Feb;154(3):689-703. doi: 10.1053/j.gastro.2017.10.012. Epub 2017 Oct 23. Gastroenterology. 2018. PMID: 29074451 Free PMC article.
Roles of autophagy and metabolism in pancreatic cancer cell adaptation to environmental challenges.
Maertin S, Elperin JM, Lotshaw E, Sendler M, Speakman SD, Takakura K, Reicher BM, Mareninova OA, Grippo PJ, Mayerle J, Lerch MM, Gukovskaya AS. Maertin S, et al. Among authors: elperin jm. Am J Physiol Gastrointest Liver Physiol. 2017 Nov 1;313(5):G524-G536. doi: 10.1152/ajpgi.00138.2017. Epub 2017 Jul 13. Am J Physiol Gastrointest Liver Physiol. 2017. PMID: 28705806 Free PMC article.
Ethanol inhibits pancreatic acinar cell autophagy through upregulation of ATG4B, mediating pathological responses of alcoholic pancreatitis.
Mareninova OA, Gretler SR, Lee GE, Pimienta M, Qin Y, Elperin JM, Ni J, Razga Z, Gukovskaya AS, Gukovsky I. Mareninova OA, et al. Among authors: elperin jm. Am J Physiol Gastrointest Liver Physiol. 2023 Sep 1;325(3):G265-G278. doi: 10.1152/ajpgi.00053.2023. Epub 2023 Jul 11. Am J Physiol Gastrointest Liver Physiol. 2023. PMID: 37431575