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Mps1 Phosphorylates Its N-Terminal Extension to Relieve Autoinhibition and Activate the Spindle Assembly Checkpoint.
Combes G, Barysz H, Garand C, Gama Braga L, Alharbi I, Thebault P, Murakami L, Bryne DP, Stankovic S, Eyers PA, Bolanos-Garcia VM, Earnshaw WC, Maciejowski J, Jallepalli PV, Elowe S. Combes G, et al. Among authors: elowe s. Curr Biol. 2018 Mar 19;28(6):872-883.e5. doi: 10.1016/j.cub.2018.02.002. Epub 2018 Mar 1. Curr Biol. 2018. PMID: 29502948 Free PMC article.
Characterization of spindle checkpoint kinase Mps1 reveals domain with functional and structural similarities to tetratricopeptide repeat motifs of Bub1 and BubR1 checkpoint kinases.
Lee S, Thebault P, Freschi L, Beaufils S, Blundell TL, Landry CR, Bolanos-Garcia VM, Elowe S. Lee S, et al. Among authors: elowe s. J Biol Chem. 2012 Feb 17;287(8):5988-6001. doi: 10.1074/jbc.M111.307355. Epub 2011 Dec 20. J Biol Chem. 2012. PMID: 22187426 Free PMC article.
Playing polo during mitosis: PLK1 takes the lead.
Combes G, Alharbi I, Braga LG, Elowe S. Combes G, et al. Among authors: elowe s. Oncogene. 2017 Aug 24;36(34):4819-4827. doi: 10.1038/onc.2017.113. Epub 2017 Apr 24. Oncogene. 2017. PMID: 28436952 Review.
ZNF768 links oncogenic RAS to cellular senescence.
Villot R, Poirier A, Bakan I, Boulay K, Fernández E, Devillers R, Gama-Braga L, Tribouillard L, Gagné A, Duchesne É, Caron D, Bérubé JS, Bérubé JC, Coulombe Y, Orain M, Gélinas Y, Gobeil S, Bossé Y, Masson JY, Elowe S, Bilodeau S, Manem V, Joubert P, Mallette FA, Laplante M. Villot R, et al. Among authors: elowe s. Nat Commun. 2021 Aug 17;12(1):4841. doi: 10.1038/s41467-021-24932-w. Nat Commun. 2021. PMID: 34404770 Free PMC article.
A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties.
Murphy JM, Zhang Q, Young SN, Reese ML, Bailey FP, Eyers PA, Ungureanu D, Hammaren H, Silvennoinen O, Varghese LN, Chen K, Tripaydonis A, Jura N, Fukuda K, Qin J, Nimchuk Z, Mudgett MB, Elowe S, Gee CL, Liu L, Daly RJ, Manning G, Babon JJ, Lucet IS. Murphy JM, et al. Among authors: elowe s. Biochem J. 2014 Jan 15;457(2):323-34. doi: 10.1042/BJ20131174. Biochem J. 2014. PMID: 24107129 Free PMC article.
Moonlighting at the Centrosome: RXRα Turns to Plk1.
Dos Santos A, Elowe S. Dos Santos A, et al. Among authors: elowe s. Dev Cell. 2020 Dec 21;55(6):672-674. doi: 10.1016/j.devcel.2020.11.027. Dev Cell. 2020. PMID: 33352140 Free article.
41 results