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Conformationally Defined Rexinoids for the Prevention of Inflammation and Nonmelanoma Skin Cancers.
Atigadda VR, Kashyap MP, Yang Z, Chattopadhyay D, Melo N, Sinha R, Belyaeva OV, Chou CF, Chang PL, Kedishvili NY, Grubbs CJ, Renfrow MB, Muccio DD, Elmets CA, Athar M. Atigadda VR, et al. Among authors: elmets ca. J Med Chem. 2022 Nov 10;65(21):14409-14423. doi: 10.1021/acs.jmedchem.2c00735. Epub 2022 Nov 1. J Med Chem. 2022. PMID: 36318154 Free PMC article.
Next-generation retinoid X receptor agonists increase ATRA signaling in organotypic epithelium cultures and have distinct effects on receptor dynamics.
Melo N, Belyaeva OV, Berger WK, Halasz L, Yu J, Pilli N, Yang Z, Klyuyeva AV, Elmets CA, Atigadda V, Muccio DD, Kane MA, Nagy L, Kedishvili NY, Renfrow MB. Melo N, et al. Among authors: elmets ca. J Biol Chem. 2023 Jan;299(1):102746. doi: 10.1016/j.jbc.2022.102746. Epub 2022 Nov 24. J Biol Chem. 2023. PMID: 36436565 Free PMC article.
Mechanism underlying follicular hyperproliferation and oncogenesis in hidradenitis suppurativa.
Jin L, Kashyap MP, Chen Y, Khan J, Guo Y, Chen JQ, Lee MB, Weng Z, Oak A, Patcha P, Mayo T, Sinha R, Atigadda V, Mukhtar SM, Deshane JS, Raman C, Elston C, Elewski BE, Elmets CA, Athar M. Jin L, et al. Among authors: elmets ca. iScience. 2023 May 19;26(6):106896. doi: 10.1016/j.isci.2023.106896. eCollection 2023 Jun 16. iScience. 2023. PMID: 37332597 Free PMC article.
Epigenetic switch reshapes epithelial progenitor cell signatures and drives inflammatory pathogenesis in hidradenitis suppurativa.
Jin L, Chen Y, Muzaffar S, Li C, Mier-Aguilar CA, Khan J, Kashyap MP, Liu S, Srivastava R, Deshane JS, Townes TM, Elewski BE, Elmets CA, Crossman DK, Raman C, Athar M. Jin L, et al. Among authors: elmets ca. Proc Natl Acad Sci U S A. 2023 Dec 5;120(49):e2315096120. doi: 10.1073/pnas.2315096120. Epub 2023 Nov 27. Proc Natl Acad Sci U S A. 2023. PMID: 38011564 Free PMC article.
244 results