Elliott PR - Search Results

1

Molecular basis and regulation of OTULIN-LUBAC interaction.

Elliott PR, Nielsen SV, Marco-Casanova P, Fiil BK, Keusekotten K, Mailand N, Freund SM, Gyrd-Hansen M, Komander D. Elliott PR, et al. Mol Cell. 2014 May 8;54(3):335-48. doi: 10.1016/j.molcel.2014.03.018. Epub 2014 Apr 10. Mol Cell. 2014. PMID: 24726323 Free PMC article.

2

OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis.

Mevissen TE, Hospenthal MK, Geurink PP, Elliott PR, Akutsu M, Arnaudo N, Ekkebus R, Kulathu Y, Wauer T, El Oualid F, Freund SM, Ovaa H, Komander D. Mevissen TE, et al. Among authors: elliott pr. Cell. 2013 Jul 3;154(1):169-84. doi: 10.1016/j.cell.2013.05.046. Cell. 2013. PMID: 23827681 Free PMC article.

3

Assembly and specific recognition of k29- and k33-linked polyubiquitin.

Michel MA, Elliott PR, Swatek KN, Simicek M, Pruneda JN, Wagstaff JL, Freund SM, Komander D. Michel MA, et al. Among authors: elliott pr. Mol Cell. 2015 Apr 2;58(1):95-109. doi: 10.1016/j.molcel.2015.01.042. Epub 2015 Mar 5. Mol Cell. 2015. PMID: 25752577 Free PMC article.

4

Regulation of Met1-linked polyubiquitin signalling by the deubiquitinase OTULIN.

Elliott PR, Komander D. Elliott PR, et al. FEBS J. 2016 Jan;283(1):39-53. doi: 10.1111/febs.13547. Epub 2015 Nov 2. FEBS J. 2016. PMID: 26503766 Free PMC article. Review.

5

CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling.

Hrdinka M, Fiil BK, Zucca M, Leske D, Bagola K, Yabal M, Elliott PR, Damgaard RB, Komander D, Jost PJ, Gyrd-Hansen M. Hrdinka M, et al. Among authors: elliott pr. Cell Rep. 2016 Mar 29;14(12):2846-58. doi: 10.1016/j.celrep.2016.02.062. Epub 2016 Mar 17. Cell Rep. 2016. PMID: 26997266 Free PMC article.

6

The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.

Damgaard RB, Walker JA, Marco-Casanova P, Morgan NV, Titheradge HL, Elliott PR, McHale D, Maher ER, McKenzie ANJ, Komander D. Damgaard RB, et al. Among authors: elliott pr. Cell. 2016 Aug 25;166(5):1215-1230.e20. doi: 10.1016/j.cell.2016.07.019. Epub 2016 Aug 11. Cell. 2016. PMID: 27523608 Free PMC article.

7

SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.

Elliott PR, Leske D, Hrdinka M, Bagola K, Fiil BK, McLaughlin SH, Wagstaff J, Volkmar N, Christianson JC, Kessler BM, Freund SM, Komander D, Gyrd-Hansen M. Elliott PR, et al. Mol Cell. 2016 Sep 15;63(6):990-1005. doi: 10.1016/j.molcel.2016.08.001. Epub 2016 Aug 30. Mol Cell. 2016. PMID: 27591049 Free PMC article.

8

A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN.

Weber A, Elliott PR, Pinto-Fernandez A, Bonham S, Kessler BM, Komander D, El Oualid F, Krappmann D. Weber A, et al. Among authors: elliott pr. Cell Chem Biol. 2017 Oct 19;24(10):1299-1313.e7. doi: 10.1016/j.chembiol.2017.08.006. Epub 2017 Sep 14. Cell Chem Biol. 2017. PMID: 28919039 Free PMC article.

9

Enzymatic Assembly of Ubiquitin Chains.

Michel MA, Komander D, Elliott PR. Michel MA, et al. Among authors: elliott pr. Methods Mol Biol. 2018;1844:73-84. doi: 10.1007/978-1-4939-8706-1_6. Methods Mol Biol. 2018. PMID: 30242704

10

OTULIN deficiency in ORAS causes cell type-specific LUBAC degradation, dysregulated TNF signalling and cell death.

Damgaard RB, Elliott PR, Swatek KN, Maher ER, Stepensky P, Elpeleg O, Komander D, Berkun Y. Damgaard RB, et al. Among authors: elliott pr. EMBO Mol Med. 2019 Mar;11(3):e9324. doi: 10.15252/emmm.201809324. EMBO Mol Med. 2019. PMID: 30804083 Free PMC article.

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