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Inhibition of PDIA3 in club cells attenuates osteopontin production and lung fibrosis.
Kumar A, Elko E, Bruno SR, Mark ZF, Chamberlain N, Mihavics BK, Chandrasekaran R, Walzer J, Ruban M, Gold C, Lam YW, Ghandikota S, Jegga AG, Gomez JL, Janssen-Heininger YM, Anathy V. Kumar A, et al. Among authors: elko e. Thorax. 2022 Jul;77(7):669-678. doi: 10.1136/thoraxjnl-2021-216882. Epub 2021 Aug 16. Thorax. 2022. PMID: 34400514 Free PMC article.
Reducing protein oxidation reverses lung fibrosis.
Anathy V, Lahue KG, Chapman DG, Chia SB, Casey DT, Aboushousha R, van der Velden JLJ, Elko E, Hoffman SM, McMillan DH, Jones JT, Nolin JD, Abdalla S, Schneider R, Seward DJ, Roberson EC, Liptak MD, Cousins ME, Butnor KJ, Taatjes DJ, Budd RC, Irvin CG, Ho YS, Hakem R, Brown KK, Matsui R, Bachschmid MM, Gomez JL, Kaminski N, van der Vliet A, Janssen-Heininger YMW. Anathy V, et al. Among authors: elko e. Nat Med. 2018 Aug;24(8):1128-1135. doi: 10.1038/s41591-018-0090-y. Epub 2018 Jul 9. Nat Med. 2018. PMID: 29988126 Free PMC article.
Peroxiredoxins and Beyond; Redox Systems Regulating Lung Physiology and Disease.
Elko EA, Cunniff B, Seward DJ, Chia SB, Aboushousha R, van de Wetering C, van der Velden J, Manuel A, Shukla A, Heintz NH, Anathy V, van der Vliet A, Janssen-Heininger YMW. Elko EA, et al. Antioxid Redox Signal. 2019 Nov 10;31(14):1070-1091. doi: 10.1089/ars.2019.7752. Epub 2019 Apr 5. Antioxid Redox Signal. 2019. PMID: 30799628 Free PMC article. Review.
Dysregulation of the glutaredoxin/S-glutathionylation redox axis in lung diseases.
Chia SB, Elko EA, Aboushousha R, Manuel AM, van de Wetering C, Druso JE, van der Velden J, Seward DJ, Anathy V, Irvin CG, Lam YW, van der Vliet A, Janssen-Heininger YMW. Chia SB, et al. Among authors: elko ea. Am J Physiol Cell Physiol. 2020 Feb 1;318(2):C304-C327. doi: 10.1152/ajpcell.00410.2019. Epub 2019 Nov 6. Am J Physiol Cell Physiol. 2020. PMID: 31693398 Free PMC article.
Glutathionylation chemistry promotes interleukin-1 beta-mediated glycolytic reprogramming and pro-inflammatory signaling in lung epithelial cells.
Aboushousha R, Elko E, Chia SB, Manuel AM, van de Wetering C, van der Velden J, MacPherson M, Erickson C, Reisz JA, D'Alessandro A, Wouters EFM, Reynaert NL, Lam YW, Anathy V, van der Vliet A, Seward DJ, Janssen-Heininger YMW. Aboushousha R, et al. Among authors: elko e. FASEB J. 2021 May;35(5):e21525. doi: 10.1096/fj.202002687RR. FASEB J. 2021. PMID: 33817836 Free PMC article.
Glutathione S-transferases and their implications in the lung diseases asthma and chronic obstructive pulmonary disease: Early life susceptibility?
van de Wetering C, Elko E, Berg M, Schiffers CHJ, Stylianidis V, van den Berge M, Nawijn MC, Wouters EFM, Janssen-Heininger YMW, Reynaert NL. van de Wetering C, et al. Among authors: elko e. Redox Biol. 2021 Jul;43:101995. doi: 10.1016/j.redox.2021.101995. Epub 2021 May 2. Redox Biol. 2021. PMID: 33979767 Free PMC article. Review.
33 results