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miR-216 and miR-217 expression is reduced in transgenic mouse models of pancreatic adenocarcinoma, knockout of miR-216/miR-217 host gene is embryonic lethal.
Azevedo-Pouly AC, Sutaria DS, Jiang J, Elgamal OA, Amari F, Allard D, Grippo PJ, Coppola V, Schmittgen TD. Azevedo-Pouly AC, et al. Among authors: elgamal oa. Funct Integr Genomics. 2017 May;17(2-3):203-212. doi: 10.1007/s10142-016-0512-1. Epub 2016 Aug 19. Funct Integr Genomics. 2017. PMID: 27541609 Free PMC article.
Comprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cells.
Zhu X, Badawi M, Pomeroy S, Sutaria DS, Xie Z, Baek A, Jiang J, Elgamal OA, Mo X, Perle K, Chalmers J, Schmittgen TD, Phelps MA. Zhu X, et al. Among authors: elgamal oa. J Extracell Vesicles. 2017 Jun 6;6(1):1324730. doi: 10.1080/20013078.2017.1324730. eCollection 2017. J Extracell Vesicles. 2017. PMID: 28717420 Free PMC article.
Low active loading of cargo into engineered extracellular vesicles results in inefficient miRNA mimic delivery.
Sutaria DS, Jiang J, Elgamal OA, Pomeroy SM, Badawi M, Zhu X, Pavlovicz R, Azevedo-Pouly ACP, Chalmers J, Li C, Phelps MA, Schmittgen TD. Sutaria DS, et al. Among authors: elgamal oa. J Extracell Vesicles. 2017 Jun 14;6(1):1333882. doi: 10.1080/20013078.2017.1333882. eCollection 2017. J Extracell Vesicles. 2017. PMID: 28717424 Free PMC article.
Inhibition of Enhancer of Zeste Homolog 2 Induces Blast Differentiation, Impairs Engraftment and Prolongs Survival in Murine Models of Acute Myeloid Leukemia.
Fobare S, Elgamal OA, Wunderlich M, Stahl E, Mehmood A, Furby C, Lerma JR, Sesterhenn TM, Pan J, Rai J, Johnstone ME, Abdul-Aziz A, Johnson ML, Rai SN, Byrd JC, Hertlein E. Fobare S, et al. Among authors: elgamal oa. Cancers (Basel). 2024 Jan 29;16(3):569. doi: 10.3390/cancers16030569. Cancers (Basel). 2024. PMID: 38339323 Free PMC article.
11 results