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New Paradigm in NKT Cell Antigens: MCS-0208 (2-(Hydroxymethyl)phenylthio-phytoceramide) - an Aryl-Phytoceramide Compound with a Single Hydroxyl Group Stimulates NKT Cells.
Borràs-Tudurí R, Alcaide A, Aspeslag S, Usero L, Serra C, Roura-Mir C, Elewaut D, Llebaria A. Borràs-Tudurí R, et al. Among authors: elewaut d. ChemMedChem. 2021 Aug 19;16(16):2491-2496. doi: 10.1002/cmdc.202000992. Epub 2021 Jun 17. ChemMedChem. 2021. PMID: 33821540 Free PMC article.
NKT cells: manipulable managers of joint inflammation.
Coppieters K, Dewint P, Van Beneden K, Jacques P, Seeuws S, Verbruggen G, Deforce D, Elewaut D. Coppieters K, et al. Among authors: elewaut d. Rheumatology (Oxford). 2007 Apr;46(4):565-71. doi: 10.1093/rheumatology/kel437. Epub 2007 Feb 16. Rheumatology (Oxford). 2007. PMID: 17307755 Review.
Synthesis and in vitro evaluation of alpha-GalCer epimers.
Trappeniers M, Goormans S, Van Beneden K, Decruy T, Linclau B, Al-Shamkhani A, Elliott T, Ottensmeier C, Werner JM, Elewaut D, Van Calenbergh S. Trappeniers M, et al. Among authors: elewaut d. ChemMedChem. 2008 Jul;3(7):1061-70. doi: 10.1002/cmdc.200800021. ChemMedChem. 2008. PMID: 18418814
The synthesis and in vivo evaluation of 2',2'-difluoro KRN7000.
Leung L, Tomassi C, Van Beneden K, Decruy T, Trappeniers M, Elewaut D, Gao Y, Elliott T, Al-Shamkhani A, Ottensmeier C, Werner JM, Williams A, Van Calenbergh S, Linclau B. Leung L, et al. Among authors: elewaut d. ChemMedChem. 2009 Mar;4(3):329-34. doi: 10.1002/cmdc.200800348. ChemMedChem. 2009. PMID: 19137519
A single early activation of invariant NK T cells confers long-term protection against collagen-induced arthritis in a ligand-specific manner.
Coppieters K, Van Beneden K, Jacques P, Dewint P, Vervloet A, Vander Cruyssen B, Van Calenbergh S, Chen G, Franck RW, Verbruggen G, Deforce D, Matthys P, Tsuji M, Rottiers P, Elewaut D. Coppieters K, et al. Among authors: elewaut d. J Immunol. 2007 Aug 15;179(4):2300-9. doi: 10.4049/jimmunol.179.4.2300. J Immunol. 2007. PMID: 17675491
355 results