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Patient-derived tumor organoids with p53 mutations, and not wild-type p53, are sensitive to synergistic combination PARP inhibitor treatment.
Madorsky Rowdo FP, Xiao G, Khramtsova GF, Nguyen J, Olopade OI, Martini R, Stonaker B, Boateng R, Oppong JK, Adjei EK, Awuah B, Kyei I, Aitpillah FS, Adinku MO, Ankomah K, Osei-Bonsu EB, Gyan KK, Altorki NK, Cheng E, Ginter PS, Hoda S, Newman L, Elemento O, Davis MB, Martin ML, Bargonetti J. Madorsky Rowdo FP, et al. Among authors: elemento o. bioRxiv [Preprint]. 2023 Jun 22:2023.06.22.544406. doi: 10.1101/2023.06.22.544406. bioRxiv. 2023. PMID: 38076873 Free PMC article. Updated. Preprint.
Immune reprogramming via PD-1 inhibition enhances early-stage lung cancer survival.
Markowitz GJ, Havel LS, Crowley MJ, Ban Y, Lee SB, Thalappillil JS, Narula N, Bhinder B, Elemento O, Wong ST, Gao D, Altorki NK, Mittal V. Markowitz GJ, et al. Among authors: elemento o. JCI Insight. 2018 Jul 12;3(13):e96836. doi: 10.1172/jci.insight.96836. JCI Insight. 2018. PMID: 29997286 Free PMC article.
Differential Contributions of Pre- and Post-EMT Tumor Cells in Breast Cancer Metastasis.
Lourenco AR, Ban Y, Crowley MJ, Lee SB, Ramchandani D, Du W, Elemento O, George JT, Jolly MK, Levine H, Sheng J, Wong ST, Altorki NK, Gao D. Lourenco AR, et al. Among authors: elemento o. Cancer Res. 2020 Jan 15;80(2):163-169. doi: 10.1158/0008-5472.CAN-19-1427. Epub 2019 Nov 8. Cancer Res. 2020. PMID: 31704888 Free PMC article.
Identification of Distinct Heterogenic Subtypes and Molecular Signatures Associated with African Ancestry in Triple Negative Breast Cancer Using Quantified Genetic Ancestry Models in Admixed Race Populations.
Davis M, Martini R, Newman L, Elemento O, White J, Verma A, Datta I, Adrianto I, Chen Y, Gardner K, Kim HG, Colomb WD, Eltoum IE, Frost AR, Grizzle WE, Sboner A, Manne U, Yates C. Davis M, et al. Among authors: elemento o. Cancers (Basel). 2020 May 13;12(5):1220. doi: 10.3390/cancers12051220. Cancers (Basel). 2020. PMID: 32414099 Free PMC article.
Social and Clinical Determinants of COVID-19 Outcomes: Modeling Real-World Data from a Pandemic Epicenter.
Manohar J, Abedian S, Martini R, Kulm S, Salvatore M, Ho K, Christos P, Campion T, Imperato-McGinley J, Ibrahim S, Evering TH, Phillips E, Tamimi R, Bea V, Balogun OD, Sboner A, Elemento O, Davis MB. Manohar J, et al. Among authors: elemento o. medRxiv [Preprint]. 2021 Apr 7:2021.04.06.21254728. doi: 10.1101/2021.04.06.21254728. medRxiv. 2021. PMID: 33851193 Free PMC article. Preprint.
Neoadjuvant durvalumab with or without stereotactic body radiotherapy in patients with early-stage non-small-cell lung cancer: a single-centre, randomised phase 2 trial.
Altorki NK, McGraw TE, Borczuk AC, Saxena A, Port JL, Stiles BM, Lee BE, Sanfilippo NJ, Scheff RJ, Pua BB, Gruden JF, Christos PJ, Spinelli C, Gakuria J, Uppal M, Binder B, Elemento O, Ballman KV, Formenti SC. Altorki NK, et al. Among authors: elemento o. Lancet Oncol. 2021 Jun;22(6):824-835. doi: 10.1016/S1470-2045(21)00149-2. Epub 2021 May 18. Lancet Oncol. 2021. PMID: 34015311 Clinical Trial.
Next generation patient derived tumor organoids.
Podaza E, Kuo HH, Nguyen J, Elemento O, Martin ML. Podaza E, et al. Among authors: elemento o. Transl Res. 2022 Dec;250:84-97. doi: 10.1016/j.trsl.2022.08.003. Epub 2022 Aug 12. Transl Res. 2022. PMID: 35964899 Review.
469 results