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An FDA/CDER perspective on nonclinical testing strategies: Classical toxicology approaches and new approach methodologies (NAMs).
Avila AM, Bebenek I, Bonzo JA, Bourcier T, Davis Bruno KL, Carlson DB, Dubinion J, Elayan I, Harrouk W, Lee SL, Mendrick DL, Merrill JC, Peretz J, Place E, Saulnier M, Wange RL, Yao J, Zhao D, Brown PC. Avila AM, et al. Among authors: elayan i. Regul Toxicol Pharmacol. 2020 Jul;114:104662. doi: 10.1016/j.yrtph.2020.104662. Epub 2020 Apr 20. Regul Toxicol Pharmacol. 2020. PMID: 32325112
CDER Experience With Juvenile Animal Studies for CNS Drugs.
Fisher JE Jr, Ravindran A, Elayan I. Fisher JE Jr, et al. Among authors: elayan i. Int J Toxicol. 2019 Mar/Apr;38(2):88-95. doi: 10.1177/1091581818824313. Epub 2019 Feb 10. Int J Toxicol. 2019. PMID: 30739550
Current Topics in Postnatal Behavioral Testing.
Henck JW, Elayan I, Vorhees C, Fisher JE Jr, Morford LL. Henck JW, et al. Among authors: elayan i. Int J Toxicol. 2016 Sep;35(5):499-520. doi: 10.1177/1091581816657082. Epub 2016 Jul 4. Int J Toxicol. 2016. PMID: 27381384
A comparison of the pharmacokinetics and NMDAR antagonism-associated neurotoxicity of ketamine, (2R,6R)-hydroxynorketamine and MK-801.
Morris PJ, Burke RD, Sharma AK, Lynch DC, Lemke-Boutcher LE, Mathew S, Elayan I, Rao DB, Gould TD, Zarate CA Jr, Zanos P, Moaddel R, Thomas CJ. Morris PJ, et al. Among authors: elayan i. Neurotoxicol Teratol. 2021 Sep-Oct;87:106993. doi: 10.1016/j.ntt.2021.106993. Epub 2021 May 1. Neurotoxicol Teratol. 2021. PMID: 33945878 Free PMC article.
21 results