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MEK Inhibition Induces Therapeutic Iodine Uptake in a Murine Model of Anaplastic Thyroid Cancer.
J Nucl Med. 2019 Jul;60(7):917-923. doi: 10.2967/jnumed.118.216721. Epub 2018 Nov 21.
J Nucl Med. 2019.
PMID: 30464041
Free article.
Combined MEK and Pi3'-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo.
ElMokh O, Ruffieux-Daidié D, Roelli MA, Stooss A, Phillips WA, Gertsch J, Dettmer MS, Charles RP.
ElMokh O, et al.
Oncotarget. 2017 Apr 11;8(15):24604-24620. doi: 10.18632/oncotarget.15599.
Oncotarget. 2017.
PMID: 28445948
Free PMC article.
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PIK3CAH1047R-induced paradoxical ERK activation results in resistance to BRAFV600E specific inhibitors in BRAFV600E PIK3CAH1047R double mutant thyroid tumors.
Roelli MA, Ruffieux-Daidié D, Stooss A, ElMokh O, Phillips WA, Dettmer MS, Charles RP.
Roelli MA, et al. Among authors: elmokh o.
Oncotarget. 2017 Oct 11;8(61):103207-103222. doi: 10.18632/oncotarget.21732. eCollection 2017 Nov 28.
Oncotarget. 2017.
PMID: 29262556
Free PMC article.
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Reactive oxygen/nitrogen species contribute substantially to the antileukemia effect of APO866, a NAD lowering agent.
Cloux AJ, Aubry D, Heulot M, Widmann C, ElMokh O, Piacente F, Cea M, Nencioni A, Bellotti A, Bouzourène K, Pellegrin M, Mazzolai L, Duchosal MA, Nahimana A.
Cloux AJ, et al. Among authors: elmokh o.
Oncotarget. 2019 Nov 19;10(62):6723-6738. doi: 10.18632/oncotarget.27336. eCollection 2019 Nov 19.
Oncotarget. 2019.
PMID: 31803365
Free PMC article.
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Gut microbiota severely hampers the efficacy of NAD-lowering therapy in leukemia.
ElMokh O, Matsumoto S, Biniecka P, Bellotti A, Schaeuble K, Piacente F, Gallart-Ayala H, Ivanisevic J, Stamenkovic I, Nencioni A, Nahimana A, Duchosal MA.
ElMokh O, et al.
Cell Death Dis. 2022 Apr 8;13(4):320. doi: 10.1038/s41419-022-04763-3.
Cell Death Dis. 2022.
PMID: 35396381
Free PMC article.
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