El-Zahabi MA - Search Results

1

Design, Synthesis, and Biological Evaluation of New Potential Unusual Modified Anticancer Immunomodulators for Possible Non-Teratogenic Quinazoline-Based Thalidomide Analogs.

Mabrouk RR, Abdallah AE, Mahdy HA, El-Kalyoubi SA, Kamal OJ, Abdelghany TM, Zayed MF, Alshaeri HK, Alasmari MM, El-Zahabi MA. Mabrouk RR, et al. Among authors: el zahabi ma. Int J Mol Sci. 2023 Aug 4;24(15):12416. doi: 10.3390/ijms241512416. Int J Mol Sci. 2023. PMID: 37569792 Free PMC article.

2

Design, synthesis, and biological evaluation of new challenging thalidomide analogs as potential anticancer immunomodulatory agents.

El-Zahabi MA, Sakr H, El-Adl K, Zayed M, Abdelraheem AS, Eissa SI, Elkady H, Eissa IH. El-Zahabi MA, et al. Bioorg Chem. 2020 Nov;104:104218. doi: 10.1016/j.bioorg.2020.104218. Epub 2020 Sep 1. Bioorg Chem. 2020. PMID: 32932121

3

Design, synthesis and molecular modeling of new quinazolin-4(3H)-one based VEGFR-2 kinase inhibitors for potential anticancer evaluation.

Abdallah AE, Eissa SI, Al Ward MMS, Mabrouk RR, Mehany ABM, El-Zahabi MA. Abdallah AE, et al. Bioorg Chem. 2021 Apr;109:104695. doi: 10.1016/j.bioorg.2021.104695. Epub 2021 Feb 8. Bioorg Chem. 2021. PMID: 33647743

4

Synthesis, biological evaluation, and molecular docking of new series of antitumor and apoptosis inducers designed as VEGFR-2 inhibitors.

Abdallah AE, Mabrouk RR, Al Ward MMS, Eissa SI, Elkaeed EB, Mehany ABM, Abo-Saif MA, El-Feky OA, Alesawy MS, El-Zahabi MA. Abdallah AE, et al. J Enzyme Inhib Med Chem. 2022 Dec;37(1):573-591. doi: 10.1080/14756366.2021.2017911. J Enzyme Inhib Med Chem. 2022. PMID: 35012403 Free PMC article.

5

Design, Synthesis, Molecular Modeling and Anti-Hyperglycemic Evaluation of Quinazoline-Sulfonylurea Hybrids as Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) and Sulfonylurea Receptor (SUR) Agonists.

El-Zahabi MA, Bamanie FH, Ghareeb S, Alshaeri HK, Alasmari MM, Moustafa M, Al-Marzooki Z, Zayed MF. El-Zahabi MA, et al. Int J Mol Sci. 2022 Aug 24;23(17):9605. doi: 10.3390/ijms23179605. Int J Mol Sci. 2022. PMID: 36077003 Free PMC article.

6

New quinoline and isatin derivatives as apoptotic VEGFR-2 inhibitors: design, synthesis, anti-proliferative activity, docking, ADMET, toxicity, and MD simulation studies.

Elkaeed EB, Taghour MS, Mahdy HA, Eldehna WM, El-Deeb NM, Kenawy AM, A Alsfouk B, Dahab MA, Metwaly AM, Eissa IH, El-Zahabi MA. Elkaeed EB, et al. Among authors: el zahabi ma. J Enzyme Inhib Med Chem. 2022 Dec;37(1):2191-2205. doi: 10.1080/14756366.2022.2110869. J Enzyme Inhib Med Chem. 2022. PMID: 35975321 Free PMC article.

7

Design, synthesis, and biological evaluation of novel bioactive thalidomide analogs as anticancer immunomodulatory agents.

Kotb AR, Bakhotmah DA, Abdallah AE, Elkady H, Taghour MS, Eissa IH, El-Zahabi MA. Kotb AR, et al. Among authors: el zahabi ma. RSC Adv. 2022 Nov 22;12(52):33525-33539. doi: 10.1039/d2ra06188k. eCollection 2022 Nov 22. RSC Adv. 2022. PMID: 36505721 Free PMC article.

8

Design, synthesis, anticancer evaluation, and in silico ADMET analysis of novel thalidomide analogs as promising immunomodulatory agents.

Kotb AR, Abdallah AE, Elkady H, Eissa IH, Taghour MS, Bakhotmah DA, Abdelghany TM, El-Zahabi MA. Kotb AR, et al. Among authors: el zahabi ma. RSC Adv. 2023 Apr 3;13(16):10488-10502. doi: 10.1039/d3ra00066d. eCollection 2023 Apr 3. RSC Adv. 2023. PMID: 37021105 Free PMC article.

9

Design, synthesis, in silico studies, and biological evaluation of novel pyrimidine-5-carbonitrile derivatives as potential anti-proliferative agents, VEGFR-2 inhibitors and apoptotic inducers.

Saleh AM, Mahdy HA, El-Zahabi MA, Mehany ABM, Khalifa MM, Eissa IH. Saleh AM, et al. Among authors: el zahabi ma. RSC Adv. 2023 Jul 24;13(32):22122-22147. doi: 10.1039/d3ra04182d. eCollection 2023 Jul 19. RSC Adv. 2023. PMID: 37492514 Free PMC article.

10

Discovery of new pyrimidine-5-carbonitrile derivatives as anticancer agents targeting EGFR^WT and EGFR^T790M.

Nasser AA, Eissa IH, Oun MR, El-Zahabi MA, Taghour MS, Belal A, Saleh AM, Mehany ABM, Luesch H, Mostafa AE, Afifi WM, Rocca JR, Mahdy HA. Nasser AA, et al. Org Biomol Chem. 2020 Oct 7;18(38):7608-7634. doi: 10.1039/d0ob01557a. Org Biomol Chem. 2020. PMID: 32959865

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