El-Subbagh HI - Search Results

1

Nonclassical antifolates, part 4. 5-(2-aminothiazol-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiols as a new class of DHFR inhibitors: synthesis, biological evaluation and molecular modeling study.

Hassan GS, El-Messery SM, Al-Omary FA, Al-Rashood ST, Shabayek MI, Abulfadl YS, Habib el-SE, El-Hallouty SM, Fayad W, Mohamed KM, El-Menshawi BS, El-Subbagh HI. Hassan GS, et al. Eur J Med Chem. 2013 Aug;66:135-45. doi: 10.1016/j.ejmech.2013.05.039. Epub 2013 Jun 4. Eur J Med Chem. 2013. PMID: 23792351

2

Synthesis and biological evaluation of certain alpha,beta-unsaturated ketones and their corresponding fused pyridines as antiviral and cytotoxic agents.

El-Subbagh HI, Abu-Zaid SM, Mahran MA, Badria FA, Al-Obaid AM. El-Subbagh HI, et al. J Med Chem. 2000 Jul 27;43(15):2915-21. doi: 10.1021/jm000038m. J Med Chem. 2000. PMID: 10956199

3

Substituted quinazolines, part 2. Synthesis and in-vitro anticancer evaluation of new 2-substituted mercapto-3H-quinazoline analogs.

Khalil AA, Abdel-Hamide SG, Al-Obaid AM, El-Subbagh HI. Khalil AA, et al. Arch Pharm (Weinheim). 2003 Apr;336(2):95-103. doi: 10.1002/ardp.200390011. Arch Pharm (Weinheim). 2003. PMID: 12761762

4

Dopamine/serotonin receptor ligands. 10: SAR Studies on azecine-type dopamine receptor ligands by functional screening at human cloned D1, D2L, and D5 receptors with a microplate reader based calcium assay lead to a novel potent D1/D5 selective antagonist.

Hoefgen B, Decker M, Mohr P, Schramm AM, Rostom SA, El-Subbagh H, Schweikert PM, Rudolf DR, Kassack MU, Lehmann J. Hoefgen B, et al. J Med Chem. 2006 Jan 26;49(2):760-9. doi: 10.1021/jm050846j. J Med Chem. 2006. PMID: 16420061

5

Synthesis, dihydrofolate reductase inhibition, antitumor testing, and molecular modeling study of some new 4(3H)-quinazolinone analogs.

Al-Rashood ST, Aboldahab IA, Nagi MN, Abouzeid LA, Abdel-Aziz AA, Abdel-Hamide SG, Youssef KM, Al-Obaid AM, El-Subbagh HI. Al-Rashood ST, et al. Bioorg Med Chem. 2006 Dec 15;14(24):8608-21. doi: 10.1016/j.bmc.2006.08.030. Epub 2006 Sep 12. Bioorg Med Chem. 2006. PMID: 16971132

6

New ultra-short acting hypnotic: synthesis, biological evaluation, and metabolic profile of ethyl 8-oxo-5,6,7,8-tetrahydro-thiazolo[3,2-a][1,3]diazepin-3-carboxylate (HIE-124).

El-Subbagh HI, El-Kashef HA, Kadi AA, Abdel-Aziz AA, Hassan GS, Tettey J, Lehmann J. El-Subbagh HI, et al. Bioorg Med Chem Lett. 2008 Jan 1;18(1):72-7. doi: 10.1016/j.bmcl.2007.11.011. Epub 2007 Nov 7. Bioorg Med Chem Lett. 2008. PMID: 18023180

7

Synthesis, ultra-short acting hypnotic activity, and metabolic profile of ethyl 8-oxo-5,6,7,8-tetrahydro-thiazolo[3,2-a] [1,3]diazepin-3-carboxylate (HIE-124).

Kadi AA, El-Kashef HA, Abdel-Aziz AA, Hassan GS, Tettey J, Grant MH, Lehmann J, El-Subbagh HI. Kadi AA, et al. Arch Pharm (Weinheim). 2008 Feb;341(2):81-9. doi: 10.1002/ardp.200700132. Arch Pharm (Weinheim). 2008. PMID: 18214840

8

Substituted quinazolines, part 3. Synthesis, in vitro antitumor activity and molecular modeling study of certain 2-thieno-4(3H)-quinazolinone analogs.

Al-Obaid AM, Abdel-Hamide SG, El-Kashef HA, Abdel-Aziz AA, El-Azab AS, Al-Khamees HA, El-Subbagh HI. Al-Obaid AM, et al. Eur J Med Chem. 2009 Jun;44(6):2379-91. doi: 10.1016/j.ejmech.2008.09.015. Epub 2008 Sep 23. Eur J Med Chem. 2009. PMID: 18950904

9

Synthesis and biological evaluation of some polymethoxylated fused pyridine ring systems as antitumor agents.

Rostom SA, Hassan GS, El-Subbagh HI. Rostom SA, et al. Arch Pharm (Weinheim). 2009 Oct;342(10):584-90. doi: 10.1002/ardp.200900062. Arch Pharm (Weinheim). 2009. PMID: 19714673

10

Non-classical antifolates. Part 2: synthesis, biological evaluation, and molecular modeling study of some new 2,6-substituted-quinazolin-4-ones.

Al-Omary FA, Abou-Zeid LA, Nagi MN, Habib el-SE, Abdel-Aziz AA, El-Azab AS, Abdel-Hamide SG, Al-Omar MA, Al-Obaid AM, El-Subbagh HI. Al-Omary FA, et al. Bioorg Med Chem. 2010 Apr 15;18(8):2849-63. doi: 10.1016/j.bmc.2010.03.019. Epub 2010 Mar 12. Bioorg Med Chem. 2010. PMID: 20350811

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

75 results

Search Page