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Rational Design and Synthesis of New Selective COX-2 Inhibitors with In Vivo PGE2-Lowering Activity by Tethering Benzenesulfonamide and 1,2,3-Triazole Pharmacophores to Some NSAIDs.
Pharmaceuticals (Basel). 2022 Sep 20;15(10):1165. doi: 10.3390/ph15101165.
Pharmaceuticals (Basel). 2022.
PMID: 36297278
Free PMC article.
Rational design of biodegradable sulphonamide candidates treating septicaemia by synergistic dual inhibition of COX-2/PGE2 axis and DHPS enzyme.
El-Dershaby NH, El-Hawash SA, Kassab SE, Dabees HG, Abdel Moneim AE, Abdel Wahab IA, Abd-Alhaseeb MM, El-Miligy MMM.
El-Dershaby NH, et al.
J Enzyme Inhib Med Chem. 2022 Dec;37(1):1737-1751. doi: 10.1080/14756366.2022.2086868.
J Enzyme Inhib Med Chem. 2022.
PMID: 35707920
Free PMC article.
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