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Page 1
Dysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model.
Brazel EB, Tan A, Neville SL, Iverson AR, Udagedara SR, Cunningham BA, Sikanyika M, De Oliveira DMP, Keller B, Bohlmann L, El-Deeb IM, Ganio K, Eijkelkamp BA, McEwan AG, von Itzstein M, Maher MJ, Walker MJ, Rosch JW, McDevitt CA. Brazel EB, et al. Among authors: el deeb im. Cell Rep. 2022 Jan 11;38(2):110202. doi: 10.1016/j.celrep.2021.110202. Cell Rep. 2022. PMID: 35021083 Free PMC article.
Chemical Synergy between Ionophore PBT2 and Zinc Reverses Antibiotic Resistance.
Bohlmann L, De Oliveira DMP, El-Deeb IM, Brazel EB, Harbison-Price N, Ong CY, Rivera-Hernandez T, Ferguson SA, Cork AJ, Phan MD, Soderholm AT, Davies MR, Nimmo GR, Dougan G, Schembri MA, Cook GM, McEwan AG, von Itzstein M, McDevitt CA, Walker MJ. Bohlmann L, et al. mBio. 2018 Dec 11;9(6):e02391-18. doi: 10.1128/mBio.02391-18. mBio. 2018. PMID: 30538186 Free PMC article.
Multiple Bactericidal Mechanisms of the Zinc Ionophore PBT2.
Harbison-Price N, Ferguson SA, Heikal A, Taiaroa G, Hards K, Nakatani Y, Rennison D, Brimble MA, El-Deeb IM, Bohlmann L, McDevitt CA, von Itzstein M, Walker MJ, Cook GM. Harbison-Price N, et al. Among authors: el deeb im. mSphere. 2020 Mar 18;5(2):e00157-20. doi: 10.1128/mSphere.00157-20. mSphere. 2020. PMID: 32188750 Free PMC article.
Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsis.
De Oliveira DMP, Bohlmann L, Conroy T, Jen FE, Everest-Dass A, Hansford KA, Bolisetti R, El-Deeb IM, Forde BM, Phan MD, Lacey JA, Tan A, Rivera-Hernandez T, Brouwer S, Keller N, Kidd TJ, Cork AJ, Bauer MJ, Cook GM, Davies MR, Beatson SA, Paterson DL, McEwan AG, Li J, Schembri MA, Blaskovich MAT, Jennings MP, McDevitt CA, von Itzstein M, Walker MJ. De Oliveira DMP, et al. Among authors: el deeb im. Sci Transl Med. 2020 Nov 18;12(570):eabb3791. doi: 10.1126/scitranslmed.abb3791. Sci Transl Med. 2020. PMID: 33208501
Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection.
De Oliveira DMP, Forde BM, Phan MD, Steiner B, Zhang B, Zuegg J, El-Deeb IM, Li G, Keller N, Brouwer S, Harbison-Price N, Cork AJ, Bauer MJ, Alquethamy SF, Beatson SA, Roberts JA, Paterson DL, McEwan AG, Blaskovich MAT, Schembri MA, McDevitt CA, von Itzstein M, Walker MJ. De Oliveira DMP, et al. Among authors: el deeb im. mBio. 2022 Feb 22;13(1):e0351721. doi: 10.1128/mbio.03517-21. Epub 2022 Jan 11. mBio. 2022. PMID: 35012353 Free PMC article.
Neurodegenerative Disease Treatment Drug PBT2 Breaks Intrinsic Polymyxin Resistance in Gram-Positive Bacteria.
De Oliveira DMP, Keller B, Hayes AJ, Ong CY, Harbison-Price N, El-Deeb IM, Li G, Keller N, Bohlmann L, Brouwer S, Turner AG, Cork AJ, Jones TR, Paterson DL, McEwan AG, Davies MR, McDevitt CA, Itzstein MV, Walker MJ. De Oliveira DMP, et al. Among authors: el deeb im. Antibiotics (Basel). 2022 Mar 25;11(4):449. doi: 10.3390/antibiotics11040449. Antibiotics (Basel). 2022. PMID: 35453201 Free PMC article.
33 results