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HIF1α is a direct regulator of steroidogenesis in the adrenal gland.
Watts D, Stein J, Meneses A, Bechmann N, Neuwirth A, Kaden D, Krüger A, Sinha A, Alexaki VI, Luis Gustavo Perez-Rivas, Kircher S, Martinez A, Theodoropoulou M, Eisenhofer G, Peitzsch M, El-Armouche A, Chavakis T, Wielockx B. Watts D, et al. Cell Mol Life Sci. 2021 Apr;78(7):3577-3590. doi: 10.1007/s00018-020-03750-1. Epub 2021 Jan 19. Cell Mol Life Sci. 2021. PMID: 33464382 Free PMC article.
Adipocyte-Specific Hypoxia-Inducible Factor 2α Deficiency Exacerbates Obesity-Induced Brown Adipose Tissue Dysfunction and Metabolic Dysregulation.
García-Martín R, Alexaki VI, Qin N, Rubín de Celis MF, Economopoulou M, Ziogas A, Gercken B, Kotlabova K, Phieler J, Ehrhart-Bornstein M, Bornstein SR, Eisenhofer G, Breier G, Blüher M, Hampe J, El-Armouche A, Chatzigeorgiou A, Chung KJ, Chavakis T. García-Martín R, et al. Mol Cell Biol. 2015 Nov 16;36(3):376-93. doi: 10.1128/MCB.00430-15. Print 2016 Feb 1. Mol Cell Biol. 2015. PMID: 26572826 Free PMC article.
The ACE-2 in COVID-19: Foe or Friend?
Dalan R, Bornstein SR, El-Armouche A, Rodionov RN, Markov A, Wielockx B, Beuschlein F, Boehm BO. Dalan R, et al. Horm Metab Res. 2020 May;52(5):257-263. doi: 10.1055/a-1155-0501. Epub 2020 Apr 27. Horm Metab Res. 2020. PMID: 32340044 Free PMC article.
The longevity gene mIndy (I'm Not Dead, Yet) affects blood pressure through sympathoadrenal mechanisms.
Willmes DM, Daniels M, Kurzbach A, Lieske S, Bechmann N, Schumann T, Henke C, El-Agroudy NN, Da Costa Goncalves AC, Peitzsch M, Hofmann A, Kanczkowski W, Kräker K, Müller DN, Morawietz H, Deussen A, Wagner M, El-Armouche A, Helfand SL, Bornstein SR, de Cabo R, Bernier M, Eisenhofer G, Tank J, Jordan J, Birkenfeld AL. Willmes DM, et al. JCI Insight. 2021 Jan 25;6(2):e136083. doi: 10.1172/jci.insight.136083. JCI Insight. 2021. PMID: 33491666 Free PMC article.
HIF2α regulates the synthesis and release of epinephrine in the adrenal medulla.
Watts D, Bechmann N, Meneses A, Poutakidou IK, Kaden D, Conrad C, Krüger A, Stein J, El-Armouche A, Chavakis T, Eisenhofer G, Peitzsch M, Wielockx B. Watts D, et al. J Mol Med (Berl). 2021 Nov;99(11):1655-1666. doi: 10.1007/s00109-021-02121-y. Epub 2021 Sep 4. J Mol Med (Berl). 2021. PMID: 34480587 Free PMC article.
140 results