El-Agnaf OMA - Search Results

1

RT-QuIC Using C-Terminally Truncated α-Synuclein Forms Detects Differences in Seeding Propensity of Different Brain Regions from Synucleinopathies.

Poggiolini I, Erskine D, Vaikath NN, Ponraj J, Mansour S, Morris CM, El-Agnaf OMA. Poggiolini I, et al. Biomolecules. 2021 May 31;11(6):820. doi: 10.3390/biom11060820. Biomolecules. 2021. PMID: 34072869 Free PMC article.

2

Rotenone and elevated extracellular potassium concentration induce cell-specific fibrillation of α-synuclein in axons of cholinergic enteric neurons in the guinea-pig ileum.

Sharrad DF, Chen BN, Gai WP, Vaikath N, El-Agnaf OM, Brookes SJ. Sharrad DF, et al. Neurogastroenterol Motil. 2017 Apr;29(4). doi: 10.1111/nmo.12985. Epub 2016 Nov 7. Neurogastroenterol Motil. 2017. PMID: 27997067

3

Differential effects of immunotherapy with antibodies targeting α-synuclein oligomers and fibrils in a transgenic model of synucleinopathy.

El-Agnaf O, Overk C, Rockenstein E, Mante M, Florio J, Adame A, Vaikath N, Majbour N, Lee SJ, Kim C, Masliah E, Rissman RA. El-Agnaf O, et al. Neurobiol Dis. 2017 Aug;104:85-96. doi: 10.1016/j.nbd.2017.05.002. Epub 2017 May 2. Neurobiol Dis. 2017. PMID: 28476636 Free PMC article.

4

Skin α-synuclein deposits differ in clinical variants of synucleinopathy: an in vivo study.

Donadio V, Incensi A, El-Agnaf O, Rizzo G, Vaikath N, Del Sorbo F, Scaglione C, Capellari S, Elia A, Stanzani Maserati M, Pantieri R, Liguori R. Donadio V, et al. Sci Rep. 2018 Sep 24;8(1):14246. doi: 10.1038/s41598-018-32588-8. Sci Rep. 2018. PMID: 30250046 Free PMC article.

5

Heterogeneity in α-synuclein subtypes and their expression in cortical brain tissue lysates from Lewy body diseases and Alzheimer's disease.

Vaikath NN, Erskine D, Morris CM, Majbour NK, Vekrellis K, Li JY, El-Agnaf OMA. Vaikath NN, et al. Neuropathol Appl Neurobiol. 2019 Oct;45(6):597-608. doi: 10.1111/nan.12531. Epub 2018 Dec 3. Neuropathol Appl Neurobiol. 2019. PMID: 30422353

6

Alpha-synuclein targets GluN2A NMDA receptor subunit causing striatal synaptic dysfunction and visuospatial memory alteration.

Durante V, de Iure A, Loffredo V, Vaikath N, De Risi M, Paciotti S, Quiroga-Varela A, Chiasserini D, Mellone M, Mazzocchetti P, Calabrese V, Campanelli F, Mechelli A, Di Filippo M, Ghiglieri V, Picconi B, El-Agnaf OM, De Leonibus E, Gardoni F, Tozzi A, Calabresi P. Durante V, et al. Brain. 2019 May 1;142(5):1365-1385. doi: 10.1093/brain/awz065. Brain. 2019. PMID: 30927362 Free article.

7

Antibodies against alpha-synuclein: tools and therapies.

Vaikath NN, Hmila I, Gupta V, Erskine D, Ingelsson M, El-Agnaf OMA. Vaikath NN, et al. J Neurochem. 2019 Sep;150(5):612-625. doi: 10.1111/jnc.14713. Epub 2019 Jun 25. J Neurochem. 2019. PMID: 31055836 Free article. Review.

8

Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy.

Wu JZ, Ardah M, Haikal C, Svanbergsson A, Diepenbroek M, Vaikath NN, Li W, Wang ZY, Outeiro TF, El-Agnaf OM, Li JY. Wu JZ, et al. Transl Neurodegener. 2019 Jun 15;8:18. doi: 10.1186/s40035-019-0159-7. eCollection 2019. Transl Neurodegener. 2019. PMID: 31223479 Free PMC article.

9

Parkinson's disease biomarkers based on α-synuclein.

Fayyad M, Salim S, Majbour N, Erskine D, Stoops E, Mollenhauer B, El-Agnaf OMA. Fayyad M, et al. J Neurochem. 2019 Sep;150(5):626-636. doi: 10.1111/jnc.14809. Epub 2019 Jul 28. J Neurochem. 2019. PMID: 31265130 Free article. Review.

10

CSF or serum neurofilament light added to α-Synuclein panel discriminates Parkinson's from controls.

Oosterveld LP, Verberk IMW, Majbour NK, El-Agnaf OM, Weinstein HC, Berendse HW, Teunissen CE, van de Berg WDJ. Oosterveld LP, et al. Mov Disord. 2020 Feb;35(2):288-295. doi: 10.1002/mds.27897. Epub 2019 Nov 18. Mov Disord. 2020. PMID: 31737952 Free PMC article.

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