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Page 1
Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity.
Hailemichael Y, Johnson DH, Abdel-Wahab N, Foo WC, Bentebibel SE, Daher M, Haymaker C, Wani K, Saberian C, Ogata D, Kim ST, Nurieva R, Lazar AJ, Abu-Sbeih H, Fa'ak F, Mathew A, Wang Y, Falohun A, Trinh V, Zobniw C, Spillson C, Burks JK, Awiwi M, Elsayes K, Soto LS, Melendez BD, Davies MA, Wargo J, Curry J, Yee C, Lizee G, Singh S, Sharma P, Allison JP, Hwu P, Ekmekcioglu S, Diab A. Hailemichael Y, et al. Among authors: ekmekcioglu s. Cancer Cell. 2022 May 9;40(5):509-523.e6. doi: 10.1016/j.ccell.2022.04.004. Epub 2022 May 9. Cancer Cell. 2022. PMID: 35537412 Free PMC article.
Changes in pERK1/2 and pAKT expression in melanoma lesions after imatinib treatment.
Hwang CS, Prieto VG, Diwan AH, Lizee G, Ellerhorst JA, Ekmekcioglu S, Liu P, Eton O, Kinney SA, Grimm EA, Hwu P, Kim KB. Hwang CS, et al. Among authors: ekmekcioglu s. Melanoma Res. 2008 Aug;18(4):241-5. doi: 10.1097/CMR.0b013e3283046146. Melanoma Res. 2008. PMID: 18626307 Free PMC article. Clinical Trial.
Targeted inhibition of inducible nitric oxide synthase inhibits growth of human melanoma in vivo and synergizes with chemotherapy.
Sikora AG, Gelbard A, Davies MA, Sano D, Ekmekcioglu S, Kwon J, Hailemichael Y, Jayaraman P, Myers JN, Grimm EA, Overwijk WW. Sikora AG, et al. Among authors: ekmekcioglu s. Clin Cancer Res. 2010 Mar 15;16(6):1834-44. doi: 10.1158/1078-0432.CCR-09-3123. Epub 2010 Mar 9. Clin Cancer Res. 2010. PMID: 20215556 Free PMC article.
Association of activated c-Met with NRAS-mutated human melanomas.
Chattopadhyay C, Ellerhorst JA, Ekmekcioglu S, Greene VR, Davies MA, Grimm EA. Chattopadhyay C, et al. Among authors: ekmekcioglu s. Int J Cancer. 2012 Jul 15;131(2):E56-65. doi: 10.1002/ijc.26487. Epub 2012 Jan 11. Int J Cancer. 2012. PMID: 22020736 Free PMC article.
Oncogenic BRAF(V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma.
Khalili JS, Liu S, Rodríguez-Cruz TG, Whittington M, Wardell S, Liu C, Zhang M, Cooper ZA, Frederick DT, Li Y, Zhang M, Joseph RW, Bernatchez C, Ekmekcioglu S, Grimm E, Radvanyi LG, Davis RE, Davies MA, Wargo JA, Hwu P, Lizée G. Khalili JS, et al. Among authors: ekmekcioglu s. Clin Cancer Res. 2012 Oct 1;18(19):5329-40. doi: 10.1158/1078-0432.CCR-12-1632. Epub 2012 Jul 31. Clin Cancer Res. 2012. PMID: 22850568 Free PMC article.
Inducible nitric oxide synthase drives mTOR pathway activation and proliferation of human melanoma by reversible nitrosylation of TSC2.
Lopez-Rivera E, Jayaraman P, Parikh F, Davies MA, Ekmekcioglu S, Izadmehr S, Milton DR, Chipuk JE, Grimm EA, Estrada Y, Aguirre-Ghiso J, Sikora AG. Lopez-Rivera E, et al. Among authors: ekmekcioglu s. Cancer Res. 2014 Feb 15;74(4):1067-78. doi: 10.1158/0008-5472.CAN-13-0588. Epub 2014 Jan 7. Cancer Res. 2014. PMID: 24398473 Free PMC article.
Inflammatory IL-1β-driven JNK activation in stage III melanoma.
Qin Y, Milton DR, Oba J, Ding Z, Lizée G, Ekmekcioglu S, Grimm EA. Qin Y, et al. Among authors: ekmekcioglu s. Pigment Cell Melanoma Res. 2015 Mar;28(2):236-9. doi: 10.1111/pcmr.12348. Epub 2015 Jan 12. Pigment Cell Melanoma Res. 2015. PMID: 25546243 No abstract available.
Inflammatory Marker Testing Identifies CD74 Expression in Melanoma Tumor Cells, and Its Expression Associates with Favorable Survival for Stage III Melanoma.
Ekmekcioglu S, Davies MA, Tanese K, Roszik J, Shin-Sim M, Bassett RL Jr, Milton DR, Woodman SE, Prieto VG, Gershenwald JE, Morton DL, Hoon DS, Grimm EA. Ekmekcioglu S, et al. Clin Cancer Res. 2016 Jun 15;22(12):3016-24. doi: 10.1158/1078-0432.CCR-15-2226. Epub 2016 Jan 18. Clin Cancer Res. 2016. PMID: 26783288 Free PMC article.
Hypoxia-Driven Mechanism of Vemurafenib Resistance in Melanoma.
Qin Y, Roszik J, Chattopadhyay C, Hashimoto Y, Liu C, Cooper ZA, Wargo JA, Hwu P, Ekmekcioglu S, Grimm EA. Qin Y, et al. Among authors: ekmekcioglu s. Mol Cancer Ther. 2016 Oct;15(10):2442-2454. doi: 10.1158/1535-7163.MCT-15-0963. Epub 2016 Jul 25. Mol Cancer Ther. 2016. PMID: 27458138 Free PMC article.
69 results