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In vivo imaging of alpha-synuclein with antibody-based PET.
Roshanbin S, Xiong M, Hultqvist G, Söderberg L, Zachrisson O, Meier S, Ekmark-Lewén S, Bergström J, Ingelsson M, Sehlin D, Syvänen S. Roshanbin S, et al. Among authors: ekmark lewen s. Neuropharmacology. 2022 May 1;208:108985. doi: 10.1016/j.neuropharm.2022.108985. Epub 2022 Feb 8. Neuropharmacology. 2022. PMID: 35149134 Free article.
Accumulation of alpha-synuclein within the liver, potential role in the clearance of brain pathology associated with Parkinson's disease.
Reyes JF, Ekmark-Léwen S, Perdiki M, Klingstedt T, Hoffmann A, Wiechec E, Nilsson P, Nilsson KPR, Alafuzoff I, Ingelsson M, Hallbeck M. Reyes JF, et al. Among authors: ekmark lewen s. Acta Neuropathol Commun. 2021 Mar 20;9(1):46. doi: 10.1186/s40478-021-01136-3. Acta Neuropathol Commun. 2021. PMID: 33743820 Free PMC article.
Reduction of brain stem pathology and transient amelioration of early cognitive symptoms in transgenic mice treated with a monoclonal antibody against α-synuclein oligomers/protofibrils.
Ekmark-Lewén S, Aniszewska A, Molisak A, Gumucio A, Lindström V, Kahle PJ, Nordström E, Möller C, Fälting J, Lannfelt L, Bergström J, Ingelsson M. Ekmark-Lewén S, et al. Aging Brain. 2023 Jul 30;4:100086. doi: 10.1016/j.nbas.2023.100086. eCollection 2023. Aging Brain. 2023. PMID: 37559953 Free PMC article.
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