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143 results

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Page 1
Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor.
Nagabushan S, Lau LMS, Barahona P, Wong M, Sherstyuk A, Marshall GM, Tyrrell V, Wegner EA, Ekert PG, Cowley MJ, Mayoh C, Trahair TN, Crowe P, Anazodo A, Ziegler DS. Nagabushan S, et al. Among authors: ekert pg. NPJ Precis Oncol. 2021 Feb 12;5(1):9. doi: 10.1038/s41698-021-00145-8. NPJ Precis Oncol. 2021. PMID: 33580196 Free PMC article.
Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma.
Ziegler DS, Wong M, Mayoh C, Kumar A, Tsoli M, Mould E, Tyrrell V, Khuong-Quang DA, Pinese M, Gayevskiy V, Cohn RJ, Lau LMS, Reynolds M, Cox MC, Gifford A, Rodriguez M, Cowley MJ, Ekert PG, Marshall GM, Haber M. Ziegler DS, et al. Among authors: ekert pg. Br J Cancer. 2018 Sep;119(6):693-696. doi: 10.1038/s41416-018-0251-2. Epub 2018 Sep 17. Br J Cancer. 2018. PMID: 30220707 Free PMC article.
Integration of genomics, high throughput drug screening, and personalized xenograft models as a novel precision medicine paradigm for high risk pediatric cancer.
Tsoli M, Wadham C, Pinese M, Failes T, Joshi S, Mould E, Yin JX, Gayevskiy V, Kumar A, Kaplan W, Ekert PG, Saletta F, Franshaw L, Liu J, Gifford A, Weber MA, Rodriguez M, Cohn RJ, Arndt G, Tyrrell V, Haber M, Trahair T, Marshall GM, McDonald K, Cowley MJ, Ziegler DS. Tsoli M, et al. Among authors: ekert pg. Cancer Biol Ther. 2018;19(12):1078-1087. doi: 10.1080/15384047.2018.1491498. Epub 2018 Oct 9. Cancer Biol Ther. 2018. PMID: 30299205 Free PMC article.
Immune profiling of pediatric solid tumors.
Terry RL, Meyran D, Ziegler DS, Haber M, Ekert PG, Trapani JA, Neeson PJ. Terry RL, et al. Among authors: ekert pg. J Clin Invest. 2020 Jul 1;130(7):3391-3402. doi: 10.1172/JCI137181. J Clin Invest. 2020. PMID: 32538896 Free PMC article. Review.
Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer.
Wong M, Mayoh C, Lau LMS, Khuong-Quang DA, Pinese M, Kumar A, Barahona P, Wilkie EE, Sullivan P, Bowen-James R, Syed M, Martincorena I, Abascal F, Sherstyuk A, Bolanos NA, Baber J, Priestley P, Dolman MEM, Fleuren EDG, Gauthier ME, Mould EVA, Gayevskiy V, Gifford AJ, Grebert-Wade D, Strong PA, Manouvrier E, Warby M, Thomas DM, Kirk J, Tucker K, O'Brien T, Alvaro F, McCowage GB, Dalla-Pozza L, Gottardo NG, Tapp H, Wood P, Khaw SL, Hansford JR, Moore AS, Norris MD, Trahair TN, Lock RB, Tyrrell V, Haber M, Marshall GM, Ziegler DS, Ekert PG, Cowley MJ. Wong M, et al. Among authors: ekert pg. Nat Med. 2020 Nov;26(11):1742-1753. doi: 10.1038/s41591-020-1072-4. Epub 2020 Oct 5. Nat Med. 2020. PMID: 33020650
A Novel Orthotopic Patient-Derived Xenograft Model of Radiation-Induced Glioma Following Medulloblastoma.
Whitehouse JP, Howlett M, Hii H, Mayoh C, Wong M, Barahona P, Ajuyah P, White CL, Buntine MK, Dyke JM, Lee S, Valvi S, Stanley J, Andradas C, Carline B, Kuchibhotla M, Ekert PG, Cowley MJ, Gottardo NG, Endersby R. Whitehouse JP, et al. Among authors: ekert pg. Cancers (Basel). 2020 Oct 12;12(10):2937. doi: 10.3390/cancers12102937. Cancers (Basel). 2020. PMID: 33053751 Free PMC article.
Recurrent SPECC1L-NTRK fusions in pediatric sarcoma and brain tumors.
Khuong-Quang DA, Brown LM, Wong M, Mayoh C, Sexton-Oates A, Kumar A, Pinese M, Nagabushan S, Lau L, Ludlow LE, Gifford AJ, Rodriguez M, Desai J, Fox SB, Haber M, Ziegler DS, Hansford JR, Marshall GM, Cowley MJ, Ekert PG. Khuong-Quang DA, et al. Among authors: ekert pg. Cold Spring Harb Mol Case Stud. 2020 Dec 17;6(6):a005710. doi: 10.1101/mcs.a005710. Print 2020 Dec. Cold Spring Harb Mol Case Stud. 2020. PMID: 33144287 Free PMC article.
Early-phenotype CAR-T cells for the treatment of pediatric cancers.
Meyran D, Terry RL, Zhu JJ, Haber M, Ziegler DS, Ekert PG, Trapani JA, Darcy PK, Neeson PJ. Meyran D, et al. Among authors: ekert pg. Ann Oncol. 2021 Nov;32(11):1366-1380. doi: 10.1016/j.annonc.2021.07.018. Epub 2021 Aug 8. Ann Oncol. 2021. PMID: 34375680 Free article. Review.
Whole-genome sequencing facilitates patient-specific quantitative PCR-based minimal residual disease monitoring in acute lymphoblastic leukaemia, neuroblastoma and Ewing sarcoma.
Subhash VV, Huang L, Kamili A, Wong M, Chen D, Venn NC, Atkinson C, Mayoh C, Venkat P, Tyrrell V, Marshall GM, Cowley MJ, Ekert PG, Norris MD, Haber M, Henderson MJ, Sutton R, Fletcher JI, Trahair TN. Subhash VV, et al. Among authors: ekert pg. Br J Cancer. 2022 Feb;126(3):482-491. doi: 10.1038/s41416-021-01538-z. Epub 2021 Sep 1. Br J Cancer. 2022. PMID: 34471258 Free PMC article.
143 results