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The Lipophilic Purine Nucleoside-Tdp1 Inhibitor-Enhances DNA Damage Induced by Topotecan In Vitro and Potentiates the Antitumor Effect of Topotecan In Vivo.
Chernyshova IA, Zakharenko AL, Kurochkin NN, Dyrkheeva NS, Kornienko TE, Popova NA, Nikolin VP, Ilina ES, Zharkov TD, Kupryushkin MS, Oslovsky VE, Drenichev MS, Lavrik OI. Chernyshova IA, et al. Among authors: ilina es. Molecules. 2022 Dec 31;28(1):323. doi: 10.3390/molecules28010323. Molecules. 2022. PMID: 36615517 Free PMC article.
New Hybrid Compounds Combining Fragments of Usnic Acid and Thioether Are Inhibitors of Human Enzymes TDP1, TDP2 and PARP1.
Dyrkheeva NS, Filimonov AS, Luzina OA, Orlova KA, Chernyshova IA, Kornienko TE, Malakhova AA, Medvedev SP, Zakharenko AL, Ilina ES, Anarbaev RO, Naumenko KN, Klabenkova KV, Burakova EA, Stetsenko DA, Zakian SM, Salakhutdinov NF, Lavrik OI. Dyrkheeva NS, et al. Among authors: ilina es. Int J Mol Sci. 2021 Oct 20;22(21):11336. doi: 10.3390/ijms222111336. Int J Mol Sci. 2021. PMID: 34768766 Free PMC article.
The First Berberine-Based Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), an Important DNA Repair Enzyme.
Gladkova ED, Nechepurenko IV, Bredikhin RA, Chepanova AA, Zakharenko AL, Luzina OA, Ilina ES, Dyrkheeva NS, Mamontova EM, Anarbaev RO, Reynisson J, Volcho KP, Salakhutdinov NF, Lavrik OI. Gladkova ED, et al. Among authors: ilina es. Int J Mol Sci. 2020 Sep 28;21(19):7162. doi: 10.3390/ijms21197162. Int J Mol Sci. 2020. PMID: 32998385 Free PMC article.
20 results