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Vaccine-Induced Simian Immunodeficiency Virus-Specific CD8+ T-Cell Responses Focused on a Single Nef Epitope Select for Escape Variants Shortly after Infection.
Martins MA, Tully DC, Cruz MA, Power KA, Veloso de Santana MG, Bean DJ, Ogilvie CB, Gadgil R, Lima NS, Magnani DM, Ejima K, Allison DB, Piatak M Jr, Altman JD, Parks CL, Rakasz EG, Capuano S 3rd, Galler R, Bonaldo MC, Lifson JD, Allen TM, Watkins DI. Martins MA, et al. Among authors: ejima k. J Virol. 2015 Nov;89(21):10802-20. doi: 10.1128/JVI.01440-15. Epub 2015 Aug 19. J Virol. 2015. PMID: 26292326 Free PMC article.
Observational research rigour alone does not justify causal inference.
Ejima K, Li P, Smith DL Jr, Nagy TR, Kadish I, van Groen T, Dawson JA, Yang Y, Patki A, Allison DB. Ejima K, et al. Eur J Clin Invest. 2016 Dec;46(12):985-993. doi: 10.1111/eci.12681. Epub 2016 Oct 28. Eur J Clin Invest. 2016. PMID: 27711975 Free PMC article.
Vaccine-induced immune responses against both Gag and Env improve control of simian immunodeficiency virus replication in rectally challenged rhesus macaques.
Martins MA, Shin YC, Gonzalez-Nieto L, Domingues A, Gutman MJ, Maxwell HS, Castro I, Magnani DM, Ricciardi M, Pedreño-Lopez N, Bailey V, Betancourt D, Altman JD, Pauthner M, Burton DR, von Bredow B, Evans DT, Yuan M, Parks CL, Ejima K, Allison DB, Rakasz E, Barber GN, Capuano S 3rd, Lifson JD, Desrosiers RC, Watkins DI. Martins MA, et al. Among authors: ejima k. PLoS Pathog. 2017 Jul 21;13(7):e1006529. doi: 10.1371/journal.ppat.1006529. eCollection 2017 Jul. PLoS Pathog. 2017. PMID: 28732035 Free PMC article.
Mamu-B*17+ Rhesus Macaques Vaccinated with env, vif, and nef Manifest Early Control of SIVmac239 Replication.
Martins MA, Tully DC, Pedreño-Lopez N, von Bredow B, Pauthner MG, Shin YC, Yuan M, Lima NS, Bean DJ, Gonzalez-Nieto L, Domingues A, Gutman MJ, Maxwell HS, Magnani DM, Ricciardi MJ, Bailey VK, Altman JD, Burton DR, Ejima K, Allison DB, Evans DT, Rakasz EG, Parks CL, Bonaldo MC, Capuano S 3rd, Lifson JD, Desrosiers RC, Allen TM, Watkins DI. Martins MA, et al. Among authors: ejima k. J Virol. 2018 Jul 31;92(16):e00690-18. doi: 10.1128/JVI.00690-18. Print 2018 Aug 15. J Virol. 2018. PMID: 29875239 Free PMC article.
Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice.
Mao K, Quipildor GF, Tabrizian T, Novaj A, Guan F, Walters RO, Delahaye F, Hubbard GB, Ikeno Y, Ejima K, Li P, Allison DB, Salimi-Moosavi H, Beltran PJ, Cohen P, Barzilai N, Huffman DM. Mao K, et al. Among authors: ejima k. Nat Commun. 2018 Jun 19;9(1):2394. doi: 10.1038/s41467-018-04805-5. Nat Commun. 2018. PMID: 29921922 Free PMC article.
Senolytics improve physical function and increase lifespan in old age.
Xu M, Pirtskhalava T, Farr JN, Weigand BM, Palmer AK, Weivoda MM, Inman CL, Ogrodnik MB, Hachfeld CM, Fraser DG, Onken JL, Johnson KO, Verzosa GC, Langhi LGP, Weigl M, Giorgadze N, LeBrasseur NK, Miller JD, Jurk D, Singh RJ, Allison DB, Ejima K, Hubbard GB, Ikeno Y, Cubro H, Garovic VD, Hou X, Weroha SJ, Robbins PD, Niedernhofer LJ, Khosla S, Tchkonia T, Kirkland JL. Xu M, et al. Among authors: ejima k. Nat Med. 2018 Aug;24(8):1246-1256. doi: 10.1038/s41591-018-0092-9. Epub 2018 Jul 9. Nat Med. 2018. PMID: 29988130 Free PMC article.
The Frequency of Vaccine-Induced T-Cell Responses Does Not Predict the Rate of Acquisition after Repeated Intrarectal SIVmac239 Challenges in Mamu-B*08+ Rhesus Macaques.
Martins MA, Gonzalez-Nieto L, Shin YC, Domingues A, Gutman MJ, Maxwell HS, Magnani DM, Ricciardi MJ, Pedreño-Lopez N, Bailey VK, Altman JD, Parks CL, Allison DB, Ejima K, Rakasz EG, Capuano S 3rd, Desrosiers RC, Lifson JD, Watkins DI. Martins MA, et al. Among authors: ejima k. J Virol. 2019 Feb 19;93(5):e01626-18. doi: 10.1128/JVI.01626-18. Print 2019 Mar 1. J Virol. 2019. PMID: 30541854 Free PMC article.
219 results