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Neuropeptide Y1 receptor antagonism protects β-cells and improves glycemic control in type 2 diabetes.
Yang CH, Ann-Onda D, Lin X, Fynch S, Nadarajah S, Pappas EG, Liu X, Scott JW, Oakhill JS, Galic S, Shi Y, Moreno-Asso A, Smith C, Loudovaris T, Levinger I, Eizirik DL, Laybutt DR, Herzog H, Thomas HE, Loh K. Yang CH, et al. Among authors: eizirik dl. Mol Metab. 2022 Jan;55:101413. doi: 10.1016/j.molmet.2021.101413. Epub 2021 Dec 7. Mol Metab. 2022. PMID: 34890851 Free PMC article.
JunB protects β-cells from lipotoxicity via the XBP1-AKT pathway.
Cunha DA, Gurzov EN, Naamane N, Ortis F, Cardozo AK, Bugliani M, Marchetti P, Eizirik DL, Cnop M. Cunha DA, et al. Among authors: eizirik dl. Cell Death Differ. 2014 Aug;21(8):1313-24. doi: 10.1038/cdd.2014.53. Epub 2014 May 2. Cell Death Differ. 2014. PMID: 24786832 Free PMC article.
Clic4, a novel protein that sensitizes β-cells to apoptosis.
Patel D, Ythier D, Brozzi F, Eizirik DL, Thorens B. Patel D, et al. Among authors: eizirik dl. Mol Metab. 2015 Jan 20;4(4):253-64. doi: 10.1016/j.molmet.2015.01.003. eCollection 2015 Apr. Mol Metab. 2015. PMID: 25830089 Free PMC article.
Viral infections in type 1 diabetes mellitus--why the β cells?
Op de Beeck A, Eizirik DL. Op de Beeck A, et al. Among authors: eizirik dl. Nat Rev Endocrinol. 2016 May;12(5):263-273. doi: 10.1038/nrendo.2016.30. Epub 2016 Mar 29. Nat Rev Endocrinol. 2016. PMID: 27020257 Free PMC article. Review.
Pannexin-2-deficiency sensitizes pancreatic β-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo.
Berchtold LA, Miani M, Diep TA, Madsen AN, Cigliola V, Colli M, Krivokapic JM, Pociot F, Eizirik DL, Meda P, Holst B, Billestrup N, Størling J. Berchtold LA, et al. Among authors: eizirik dl. Mol Cell Endocrinol. 2017 Jun 15;448:108-121. doi: 10.1016/j.mce.2017.04.001. Epub 2017 Apr 5. Mol Cell Endocrinol. 2017. PMID: 28390953
418 results