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Anti-rheumatic colchicine phytochemical exhibits potent antiviral activities against avian and seasonal Influenza A viruses (IAVs) via targeting different stages of IAV replication cycle.
Hegazy A, Soltane R, Alasiri A, Mostafa I, Metwaly AM, Eissa IH, Mahmoud SH, Allayeh AK, Shama NMA, Khalil AA, Barre RS, El-Shazly AM, Ali MA, Martinez-Sobrido L, Mostafa A. Hegazy A, et al. Among authors: eissa ih. BMC Complement Med Ther. 2024 Jan 22;24(1):49. doi: 10.1186/s12906-023-04303-2. BMC Complement Med Ther. 2024. PMID: 38254071 Free PMC article.
Design, synthesis, molecular modeling and anti-proliferative evaluation of novel quinoxaline derivatives as potential DNA intercalators and topoisomerase II inhibitors.
Ibrahim MK, Taghour MS, Metwaly AM, Belal A, Mehany ABM, Elhendawy MA, Radwan MM, Yassin AM, El-Deeb NM, Hafez EE, ElSohly MA, Eissa IH. Ibrahim MK, et al. Among authors: eissa ih. Eur J Med Chem. 2018 Jul 15;155:117-134. doi: 10.1016/j.ejmech.2018.06.004. Epub 2018 Jun 4. Eur J Med Chem. 2018. PMID: 29885574
Design, synthesis, molecular modeling, in vivo studies and anticancer evaluation of quinazolin-4(3H)-one derivatives as potential VEGFR-2 inhibitors and apoptosis inducers.
Mahdy HA, Ibrahim MK, Metwaly AM, Belal A, Mehany ABM, El-Gamal KMA, El-Sharkawy A, Elhendawy MA, Radwan MM, Elsohly MA, Eissa IH. Mahdy HA, et al. Among authors: eissa ih. Bioorg Chem. 2020 Jan;94:103422. doi: 10.1016/j.bioorg.2019.103422. Epub 2019 Nov 12. Bioorg Chem. 2020. PMID: 31812261
Design, synthesis, molecular modeling, in vivo studies and anticancer activity evaluation of new phthalazine derivatives as potential DNA intercalators and topoisomerase II inhibitors.
El-Helby AA, Sakr H, Ayyad RR, Mahdy HA, Khalifa MM, Belal A, Rashed M, El-Sharkawy A, Metwaly AM, Elhendawy MA, Radwan MM, ElSohly MA, Eissa IH. El-Helby AA, et al. Among authors: eissa ih. Bioorg Chem. 2020 Oct;103:104233. doi: 10.1016/j.bioorg.2020.104233. Epub 2020 Aug 26. Bioorg Chem. 2020. PMID: 32882440
131 results