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Page 1
The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs.
Virtue AT, McCright SJ, Wright JM, Jimenez MT, Mowel WK, Kotzin JJ, Joannas L, Basavappa MG, Spencer SP, Clark ML, Eisennagel SH, Williams A, Levy M, Manne S, Henrickson SE, Wherry EJ, Thaiss CA, Elinav E, Henao-Mejia J. Virtue AT, et al. Among authors: eisennagel sh. Sci Transl Med. 2019 Jun 12;11(496):eaav1892. doi: 10.1126/scitranslmed.aav1892. Sci Transl Med. 2019. PMID: 31189717 Free PMC article.
Design and Optimization of Sulfone Pyrrolidine Sulfonamide Antagonists of Transient Receptor Potential Vanilloid-4 with in Vivo Activity in a Pulmonary Edema Model.
Pero JE, Matthews JM, Behm DJ, Brnardic EJ, Brooks C, Budzik BW, Costell MH, Donatelli CA, Eisennagel SH, Erhard K, Fischer MC, Holt DA, Jolivette LJ, Li H, Li P, McAtee JJ, McCleland BW, Pendrak I, Posobiec LM, Rivera KLK, Rivero RA, Roethke TJ, Sender MR, Shu A, Terrell LR, Vaidya K, Xu X, Lawhorn BG. Pero JE, et al. Among authors: eisennagel sh. J Med Chem. 2018 Dec 27;61(24):11209-11220. doi: 10.1021/acs.jmedchem.8b01344. Epub 2018 Dec 12. J Med Chem. 2018. PMID: 30500190
Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress.
Qin P, Arabacilar P, Bernard RE, Bao W, Olzinski AR, Guo Y, Lal H, Eisennagel SH, Platchek MC, Xie W, Del Rosario J, Nayal M, Lu Q, Roethke T, Schnackenberg CG, Wright F, Quaile MP, Halsey WS, Hughes AM, Sathe GM, Livi GP, Kirkpatrick RB, Qu XA, Rajpal DK, Faelth Savitski M, Bantscheff M, Joberty G, Bergamini G, Force TL, Gatto GJ Jr, Hu E, Willette RN. Qin P, et al. Among authors: eisennagel sh. J Am Heart Assoc. 2017 May 9;6(5):e004453. doi: 10.1161/JAHA.116.004453. J Am Heart Assoc. 2017. PMID: 28487390 Free PMC article.
Discovery of 1-(1,3,5-triazin-2-yl)piperidine-4-carboxamides as inhibitors of soluble epoxide hydrolase.
Thalji RK, McAtee JJ, Belyanskaya S, Brandt M, Brown GD, Costell MH, Ding Y, Dodson JW, Eisennagel SH, Fries RE, Gross JW, Harpel MR, Holt DA, Israel DI, Jolivette LJ, Krosky D, Li H, Lu Q, Mandichak T, Roethke T, Schnackenberg CG, Schwartz B, Shewchuk LM, Xie W, Behm DJ, Douglas SA, Shaw AL, Marino JP Jr. Thalji RK, et al. Among authors: eisennagel sh. Bioorg Med Chem Lett. 2013 Jun 15;23(12):3584-8. doi: 10.1016/j.bmcl.2013.04.019. Epub 2013 Apr 16. Bioorg Med Chem Lett. 2013. PMID: 23664879
Design and synthesis of polyethylene glycol-modified biphenylsulfonyl-thiophene-carboxamidine inhibitors of the complement component C1s.
Subasinghe NL, Khalil E, Travins JM, Ali F, Ballentine SK, Hufnagel HR, Pan W, Leonard K, Bone RF, Soll RM, Crysler CS, Ninan N, Kirkpatrick J, Kolpak MX, Diloreto KA, Eisennagel SH, Huebert ND, Molloy CJ, Tomczuk BE, Gaul MD. Subasinghe NL, et al. Among authors: eisennagel sh. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5303-7. doi: 10.1016/j.bmcl.2012.06.030. Epub 2012 Jun 16. Bioorg Med Chem Lett. 2012. PMID: 22795627
A functional radioreceptor assay of alpha-V-beta-3 (alphavbeta3) inhibitors in plasma: application as an ex vivo pharmacodynamic model.
Chaikin MA, Marugan JJ, De Vries GW, Baciu P, Edelman J, Ni M, Tomczuk BE, Pan W, Guo Z, Anaclerio B, Leonard K, Eisennagel SH, Molloy CJ, Manthey CL. Chaikin MA, et al. Among authors: eisennagel sh. J Biochem Biophys Methods. 2005 Dec 31;65(2-3):107-20. doi: 10.1016/j.jbbm.2005.10.004. Epub 2005 Nov 21. J Biochem Biophys Methods. 2005. PMID: 16325916