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High-Fat Diet Accelerates Carcinogenesis in a Mouse Model of Barrett's Esophagus via Interleukin 8 and Alterations to the Gut Microbiome.
Münch NS, Fang HY, Ingermann J, Maurer HC, Anand A, Kellner V, Sahm V, Wiethaler M, Baumeister T, Wein F, Einwächter H, Bolze F, Klingenspor M, Haller D, Kavanagh M, Lysaght J, Friedman R, Dannenberg AJ, Pollak M, Holt PR, Muthupalani S, Fox JG, Whary MT, Lee Y, Ren TY, Elliot R, Fitzgerald R, Steiger K, Schmid RM, Wang TC, Quante M. Münch NS, et al. Among authors: einwachter h. Gastroenterology. 2019 Aug;157(2):492-506.e2. doi: 10.1053/j.gastro.2019.04.013. Epub 2019 Apr 15. Gastroenterology. 2019. PMID: 30998992 Free PMC article.
Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma.
Mazur PK, Einwächter H, Lee M, Sipos B, Nakhai H, Rad R, Zimber-Strobl U, Strobl LJ, Radtke F, Klöppel G, Schmid RM, Siveke JT. Mazur PK, et al. Among authors: einwachter h. Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13438-43. doi: 10.1073/pnas.1002423107. Epub 2010 Jul 12. Proc Natl Acad Sci U S A. 2010. PMID: 20624967 Free PMC article.
Deletion of IκBα activates RelA to reduce acute pancreatitis in mice through up-regulation of Spi2A.
Neuhöfer P, Liang S, Einwächter H, Schwerdtfeger C, Wartmann T, Treiber M, Zhang H, Schulz HU, Dlubatz K, Lesina M, Diakopoulos KN, Wörmann S, Halangk W, Witt H, Schmid RM, Algül H. Neuhöfer P, et al. Among authors: einwachter h. Gastroenterology. 2013 Jan;144(1):192-201. doi: 10.1053/j.gastro.2012.09.058. Epub 2012 Oct 3. Gastroenterology. 2013. PMID: 23041330
The Ras inhibitors caveolin-1 and docking protein 1 activate peroxisome proliferator-activated receptor γ through spatial relocalization at helix 7 of its ligand-binding domain.
Burgermeister E, Friedrich T, Hitkova I, Regel I, Einwächter H, Zimmermann W, Röcken C, Perren A, Wright MB, Schmid RM, Seger R, Ebert MP. Burgermeister E, et al. Among authors: einwachter h. Mol Cell Biol. 2011 Aug;31(16):3497-510. doi: 10.1128/MCB.01421-10. Epub 2011 Jun 20. Mol Cell Biol. 2011. PMID: 21690289 Free PMC article.
48 results