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Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy.
Haikala HM, Anttila JM, Marques E, Raatikainen T, Ilander M, Hakanen H, Ala-Hongisto H, Savelius M, Balboa D, Von Eyss B, Eskelinen V, Munne P, Nieminen AI, Otonkoski T, Schüler J, Laajala TD, Aittokallio T, Sihto H, Mattson J, Heikkilä P, Leidenius M, Joensuu H, Mustjoki S, Kovanen P, Eilers M, Leverson JD, Klefström J. Haikala HM, et al. Among authors: eilers m. Nat Commun. 2019 Feb 6;10(1):620. doi: 10.1038/s41467-019-08541-2. Nat Commun. 2019. PMID: 30728358 Free PMC article.
Myc's broad reach.
Eilers M, Eisenman RN. Eilers M, et al. Genes Dev. 2008 Oct 15;22(20):2755-66. doi: 10.1101/gad.1712408. Genes Dev. 2008. PMID: 18923074 Free PMC article. Review.
Addicted to Myc--but why?
von Eyss B, Eilers M. von Eyss B, et al. Among authors: eilers m. Genes Dev. 2011 May 1;25(9):895-7. doi: 10.1101/gad.2053311. Genes Dev. 2011. PMID: 21536730 Free PMC article.
Deregulated MYC expression induces dependence upon AMPK-related kinase 5.
Liu L, Ulbrich J, Müller J, Wüstefeld T, Aeberhard L, Kress TR, Muthalagu N, Rycak L, Rudalska R, Moll R, Kempa S, Zender L, Eilers M, Murphy DJ. Liu L, et al. Among authors: eilers m. Nature. 2012 Mar 28;483(7391):608-12. doi: 10.1038/nature10927. Nature. 2012. PMID: 22460906
Miz1 is required to maintain autophagic flux.
Wolf E, Gebhardt A, Kawauchi D, Walz S, von Eyss B, Wagner N, Renninger C, Krohne G, Asan E, Roussel MF, Eilers M. Wolf E, et al. Among authors: eilers m. Nat Commun. 2013;4:2535. doi: 10.1038/ncomms3535. Nat Commun. 2013. PMID: 24088869 Free PMC article.
Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles.
Walz S, Lorenzin F, Morton J, Wiese KE, von Eyss B, Herold S, Rycak L, Dumay-Odelot H, Karim S, Bartkuhn M, Roels F, Wüstefeld T, Fischer M, Teichmann M, Zender L, Wei CL, Sansom O, Wolf E, Eilers M. Walz S, et al. Among authors: eilers m. Nature. 2014 Jul 24;511(7510):483-7. doi: 10.1038/nature13473. Epub 2014 Jul 9. Nature. 2014. PMID: 25043018 Free PMC article.
299 results