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Page 1
HIV nucleoside reverse transcriptase inhibitors.
Amblard F, Patel D, Michailidis E, Coats SJ, Kasthuri M, Biteau N, Tber Z, Ehteshami M, Schinazi RF. Amblard F, et al. Among authors: ehteshami m. Eur J Med Chem. 2022 Oct 5;240:114554. doi: 10.1016/j.ejmech.2022.114554. Epub 2022 Jun 20. Eur J Med Chem. 2022. PMID: 35792384 Review.
β-D-2'-C-Methyl-2,6-diaminopurine Ribonucleoside Phosphoramidates are Potent and Selective Inhibitors of Hepatitis C Virus (HCV) and Are Bioconverted Intracellularly to Bioactive 2,6-Diaminopurine and Guanosine 5'-Triphosphate Forms.
Zhou L, Zhang HW, Tao S, Bassit L, Whitaker T, McBrayer TR, Ehteshami M, Amiralaei S, Pradere U, Cho JH, Amblard F, Bobeck D, Detorio M, Coats SJ, Schinazi RF. Zhou L, et al. Among authors: ehteshami m. J Med Chem. 2015 Apr 23;58(8):3445-58. doi: 10.1021/jm501874e. Epub 2015 Apr 7. J Med Chem. 2015. PMID: 25849312 Free PMC article.
Discovery of a Series of 2'-α-Fluoro,2'-β-bromo-ribonucleosides and Their Phosphoramidate Prodrugs as Potent Pan-Genotypic Inhibitors of Hepatitis C Virus.
Mengshetti S, Zhou L, Sari O, De Schutter C, Zhang H, Cho JH, Tao S, Bassit LC, Verma K, Domaoal RA, Ehteshami M, Jiang Y, Ovadia R, Kasthuri M, Ollinger Russell O, McBrayer T, Whitaker T, Pattassery J, Pascual ML, Uher L, Lin BY, Lee S, Amblard F, Coats SJ, Schinazi RF. Mengshetti S, et al. Among authors: ehteshami m. J Med Chem. 2019 Feb 28;62(4):1859-1874. doi: 10.1021/acs.jmedchem.8b01300. Epub 2019 Feb 7. J Med Chem. 2019. PMID: 30653317 Free PMC article.
Chutes and ladders in hepatitis C nucleoside drug development.
Coats SJ, Garnier-Amblard EC, Amblard F, Ehteshami M, Amiralaei S, Zhang H, Zhou L, Boucle SR, Lu X, Bondada L, Shelton JR, Li H, Liu P, Li C, Cho JH, Chavre SN, Zhou S, Mathew J, Schinazi RF. Coats SJ, et al. Among authors: ehteshami m. Antiviral Res. 2014 Feb;102:119-47. doi: 10.1016/j.antiviral.2013.11.008. Epub 2013 Nov 23. Antiviral Res. 2014. PMID: 24275341 Free PMC article. Review.
Approaches to hepatitis C treatment and cure using NS5A inhibitors.
Kohler JJ, Nettles JH, Amblard F, Hurwitz SJ, Bassit L, Stanton RA, Ehteshami M, Schinazi RF. Kohler JJ, et al. Among authors: ehteshami m. Infect Drug Resist. 2014 Mar 5;7:41-56. doi: 10.2147/IDR.S36247. eCollection 2014. Infect Drug Resist. 2014. PMID: 24623983 Free PMC article. Review.
2'-Chloro,2'-fluoro Ribonucleotide Prodrugs with Potent Pan-genotypic Activity against Hepatitis C Virus Replication in Culture.
Zhou S, Mahmoud S, Liu P, Zhou L, Ehteshami M, Bassit L, Tao S, Domaoal RA, Sari O, Schutter C, Amiralaei S, Khalil A, Ollinger Russell O, McBrayer T, Whitaker T, Abou-Taleb N, Amblard F, Coats SJ, Schinazi RF. Zhou S, et al. Among authors: ehteshami m. J Med Chem. 2017 Jul 13;60(13):5424-5437. doi: 10.1021/acs.jmedchem.7b00067. Epub 2017 Jun 26. J Med Chem. 2017. PMID: 28595015
42 results