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Page 1
PNC-27, a Chimeric p53-Penetratin Peptide Binds to HDM-2 in a p53 Peptide-like Structure, Induces Selective Membrane-Pore Formation and Leads to Cancer Cell Lysis.
Sarafraz-Yazdi E, Mumin S, Cheung D, Fridman D, Lin B, Wong L, Rosal R, Rudolph R, Frenkel M, Thadi A, Morano WF, Bowne WB, Pincus MR, Michl J. Sarafraz-Yazdi E, et al. Biomedicines. 2022 Apr 20;10(5):945. doi: 10.3390/biomedicines10050945. Biomedicines. 2022. PMID: 35625682 Free PMC article.
Emerging Role of MDM2 as Target for Anti-Cancer Therapy: A Review.
Shaikh MF, Morano WF, Lee J, Gleeson E, Babcock BD, Michl J, Sarafraz-Yazdi E, Pincus MR, Bowne WB. Shaikh MF, et al. Among authors: sarafraz yazdi e. Ann Clin Lab Sci. 2016 Dec;46(6):627-634. Ann Clin Lab Sci. 2016. PMID: 27993876 Review.
The anti-cancer peptide, PNC-27, induces tumor cell necrosis of a poorly differentiated non-solid tissue human leukemia cell line that depends on expression of HDM-2 in the plasma membrane of these cells.
Davitt K, Babcock BD, Fenelus M, Poon CK, Sarkar A, Trivigno V, Zolkind PA, Matthew SM, Grin'kina N, Orynbayeva Z, Shaikh MF, Adler V, Michl J, Sarafraz-Yazdi E, Pincus MR, Bowne WB. Davitt K, et al. Among authors: sarafraz yazdi e. Ann Clin Lab Sci. 2014 Summer;44(3):241-8. Ann Clin Lab Sci. 2014. PMID: 25117093
16 results