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Quantitative determination of zebularine (NSC 309132), a DNA methyltransferase inhibitor, and three metabolites in murine plasma by high-performance liquid chromatography coupled with on-line radioactivity detection.
Beumer JH, Joseph E, Egorin MJ, Covey JM, Eiseman JL. Beumer JH, et al. Among authors: egorin mj. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Feb 2;831(1-2):147-55. doi: 10.1016/j.jchromb.2005.11.048. Epub 2005 Dec 20. J Chromatogr B Analyt Technol Biomed Life Sci. 2006. PMID: 16364698
Concentrations of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine (FdCyd) and its cytotoxic metabolites in plasma of patients treated with FdCyd and tetrahydrouridine (THU).
Beumer JH, Parise RA, Newman EM, Doroshow JH, Synold TW, Lenz HJ, Egorin MJ. Beumer JH, et al. Among authors: egorin mj. Cancer Chemother Pharmacol. 2008 Jul;62(2):363-8. doi: 10.1007/s00280-007-0603-8. Epub 2007 Sep 26. Cancer Chemother Pharmacol. 2008. PMID: 17899082 Clinical Trial.
349 results