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Stromal cell protein kinase C-β inhibition enhances chemosensitivity in B cell malignancies and overcomes drug resistance.
Park E, Chen J, Moore A, Mangolini M, Santoro A, Boyd JR, Schjerven H, Ecker V, Buchner M, Williamson JC, Lehner PJ, Gasparoli L, Williams O, Bloehdorn J, Stilgenbauer S, Leitges M, Egle A, Schmidt-Supprian M, Frietze S, Ringshausen I. Park E, et al. Among authors: egle a. Sci Transl Med. 2020 Jan 15;12(526):eaax9340. doi: 10.1126/scitranslmed.aax9340. Sci Transl Med. 2020. PMID: 31941829 Free PMC article.
Protein kinase c-β-dependent activation of NF-κB in stromal cells is indispensable for the survival of chronic lymphocytic leukemia B cells in vivo.
Lutzny G, Kocher T, Schmidt-Supprian M, Rudelius M, Klein-Hitpass L, Finch AJ, Dürig J, Wagner M, Haferlach C, Kohlmann A, Schnittger S, Seifert M, Wanninger S, Zaborsky N, Oostendorp R, Ruland J, Leitges M, Kuhnt T, Schäfer Y, Lampl B, Peschel C, Egle A, Ringshausen I. Lutzny G, et al. Among authors: egle a. Cancer Cell. 2013 Jan 14;23(1):77-92. doi: 10.1016/j.ccr.2012.12.003. Cancer Cell. 2013. PMID: 23328482 Free PMC article.
Bim and Bmf in tissue homeostasis and malignant disease.
Piñon JD, Labi V, Egle A, Villunger A. Piñon JD, et al. Among authors: egle a. Oncogene. 2008 Dec;27 Suppl 1(Suppl 1):S41-52. doi: 10.1038/onc.2009.42. Oncogene. 2008. PMID: 19641506 Free PMC article. Review.
160 results