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Page 1
KMT2C methyltransferase domain regulated INK4A expression suppresses prostate cancer metastasis.
Limberger T, Schlederer M, Trachtová K, Garces de Los Fayos Alonso I, Yang J, Högler S, Sternberg C, Bystry V, Oppelt J, Tichý B, Schmeidl M, Kodajova P, Jäger A, Neubauer HA, Oberhuber M, Schmalzbauer BS, Pospisilova S, Dolznig H, Wadsak W, Culig Z, Turner SD, Egger G, Lagger S, Kenner L. Limberger T, et al. Among authors: egger g. Mol Cancer. 2022 Mar 30;21(1):89. doi: 10.1186/s12943-022-01542-8. Mol Cancer. 2022. PMID: 35354467 Free PMC article.
Epidermal loss of JunB leads to a SLE phenotype due to hyper IL-6 signaling.
Pflegerl P, Vesely P, Hantusch B, Schlederer M, Zenz R, Janig E, Steiner G, Meixner A, Petzelbauer P, Wolf P, Soleiman A, Egger G, Moriggl R, Kishimoto T, Wagner EF, Kenner L. Pflegerl P, et al. Among authors: egger g. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20423-8. doi: 10.1073/pnas.0910371106. Epub 2009 Nov 16. Proc Natl Acad Sci U S A. 2009. PMID: 19918056 Free PMC article.
The cyclin-dependent kinase inhibitor p21 is a crucial target for histone deacetylase 1 as a regulator of cellular proliferation.
Zupkovitz G, Grausenburger R, Brunmeir R, Senese S, Tischler J, Jurkin J, Rembold M, Meunier D, Egger G, Lagger S, Chiocca S, Propst F, Weitzer G, Seiser C. Zupkovitz G, et al. Among authors: egger g. Mol Cell Biol. 2010 Mar;30(5):1171-81. doi: 10.1128/MCB.01500-09. Epub 2009 Dec 22. Mol Cell Biol. 2010. PMID: 20028735 Free PMC article.
Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice.
Mueller KM, Kornfeld JW, Friedbichler K, Blaas L, Egger G, Esterbauer H, Hasselblatt P, Schlederer M, Haindl S, Wagner KU, Engblom D, Haemmerle G, Kratky D, Sexl V, Kenner L, Kozlov AV, Terracciano L, Zechner R, Schuetz G, Casanova E, Pospisilik JA, Heim MH, Moriggl R. Mueller KM, et al. Among authors: egger g. Hepatology. 2011 Oct;54(4):1398-409. doi: 10.1002/hep.24509. Hepatology. 2011. PMID: 21725989 Free PMC article.
PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas.
Laimer D, Dolznig H, Kollmann K, Vesely PW, Schlederer M, Merkel O, Schiefer AI, Hassler MR, Heider S, Amenitsch L, Thallinger C, Staber PB, Simonitsch-Klupp I, Artaker M, Lagger S, Turner SD, Pileri S, Piccaluga PP, Valent P, Messana K, Landra I, Weichhart T, Knapp S, Shehata M, Todaro M, Sexl V, Höfler G, Piva R, Medico E, Ruggeri BA, Cheng M, Eferl R, Egger G, Penninger JM, Jaeger U, Moriggl R, Inghirami G, Kenner L. Laimer D, et al. Among authors: egger g. Nat Med. 2012 Nov;18(11):1699-704. doi: 10.1038/nm.2966. Epub 2012 Oct 14. Nat Med. 2012. PMID: 23064464 Free article.
The dichloromethane extract of the ethnomedicinal plant Neurolaena lobata inhibits NPM/ALK expression which is causal for anaplastic large cell lymphomagenesis.
Unger C, Popescu R, Giessrigl B, Laimer D, Heider S, Seelinger M, Diaz R, Wallnöfer B, Egger G, Hassler M, Knöfler M, Saleh L, Sahin E, Grusch M, Fritzer-Szekeres M, Dolznig H, Frisch R, Kenner L, Kopp B, Krupitza G. Unger C, et al. Among authors: egger g. Int J Oncol. 2013 Jan;42(1):338-48. doi: 10.3892/ijo.2012.1690. Epub 2012 Nov 6. Int J Oncol. 2013. PMID: 23135783
Oncogenic role of miR-155 in anaplastic large cell lymphoma lacking the t(2;5) translocation.
Merkel O, Hamacher F, Griessl R, Grabner L, Schiefer AI, Prutsch N, Baer C, Egger G, Schlederer M, Krenn PW, Hartmann TN, Simonitsch-Klupp I, Plass C, Staber PB, Moriggl R, Turner SD, Greil R, Kenner L. Merkel O, et al. Among authors: egger g. J Pathol. 2015 Aug;236(4):445-56. doi: 10.1002/path.4539. Epub 2015 Apr 27. J Pathol. 2015. PMID: 25820993 Free PMC article.
The role of AP-1 and epigenetics in ALCL.
Schiefer AI, Vesely P, Hassler MR, Egger G, Kenner L. Schiefer AI, et al. Among authors: egger g. Front Biosci (Schol Ed). 2015 Jun 1;7(2):226-35. doi: 10.2741/S436. Front Biosci (Schol Ed). 2015. PMID: 25961698 Free article. Review.
359 results