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Strategies for validation and testing of DNA methylation biomarkers.
Noehammer C, Pulverer W, Hassler MR, Hofner M, Wielscher M, Vierlinger K, Liloglou T, McCarthy D, Jensen TJ, Nygren A, Gohlke H, Trooskens G, Braspenning M, Van Criekinge W, Egger G, Weinhaeusel A. Noehammer C, et al. Among authors: egger g. Epigenomics. 2014;6(6):603-22. doi: 10.2217/epi.14.43. Epigenomics. 2014. PMID: 25531255 Review.
Identification of differential and functionally active miRNAs in both anaplastic lymphoma kinase (ALK)+ and ALK- anaplastic large-cell lymphoma.
Merkel O, Hamacher F, Laimer D, Sifft E, Trajanoski Z, Scheideler M, Egger G, Hassler MR, Thallinger C, Schmatz A, Turner SD, Greil R, Kenner L. Merkel O, et al. Among authors: egger g. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16228-33. doi: 10.1073/pnas.1009719107. Epub 2010 Aug 30. Proc Natl Acad Sci U S A. 2010. PMID: 20805506 Free PMC article.
Epigenomics of cancer - emerging new concepts.
Hassler MR, Egger G. Hassler MR, et al. Among authors: egger g. Biochimie. 2012 Nov;94(11):2219-30. doi: 10.1016/j.biochi.2012.05.007. Epub 2012 May 17. Biochimie. 2012. PMID: 22609632 Free PMC article. Review.
PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas.
Laimer D, Dolznig H, Kollmann K, Vesely PW, Schlederer M, Merkel O, Schiefer AI, Hassler MR, Heider S, Amenitsch L, Thallinger C, Staber PB, Simonitsch-Klupp I, Artaker M, Lagger S, Turner SD, Pileri S, Piccaluga PP, Valent P, Messana K, Landra I, Weichhart T, Knapp S, Shehata M, Todaro M, Sexl V, Höfler G, Piva R, Medico E, Ruggeri BA, Cheng M, Eferl R, Egger G, Penninger JM, Jaeger U, Moriggl R, Inghirami G, Kenner L. Laimer D, et al. Among authors: egger g. Nat Med. 2012 Nov;18(11):1699-704. doi: 10.1038/nm.2966. Epub 2012 Oct 14. Nat Med. 2012. PMID: 23064464 Free article.
The dichloromethane extract of the ethnomedicinal plant Neurolaena lobata inhibits NPM/ALK expression which is causal for anaplastic large cell lymphomagenesis.
Unger C, Popescu R, Giessrigl B, Laimer D, Heider S, Seelinger M, Diaz R, Wallnöfer B, Egger G, Hassler M, Knöfler M, Saleh L, Sahin E, Grusch M, Fritzer-Szekeres M, Dolznig H, Frisch R, Kenner L, Kopp B, Krupitza G. Unger C, et al. Among authors: egger g. Int J Oncol. 2013 Jan;42(1):338-48. doi: 10.3892/ijo.2012.1690. Epub 2012 Nov 6. Int J Oncol. 2013. PMID: 23135783
Cytosine 5-Hydroxymethylation of the LZTS1 Gene Is Reduced in Breast Cancer.
Wielscher M, Liou W, Pulverer W, Singer CF, Rappaport-Fuerhauser C, Kandioler D, Egger G, Weinhäusel A. Wielscher M, et al. Among authors: egger g. Transl Oncol. 2013 Dec 1;6(6):715-21. doi: 10.1593/tlo.13523. eCollection 2013 Dec 1. Transl Oncol. 2013. PMID: 24466374 Free PMC article.
359 results