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A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma.
Haugaard-Kedström LM, Clemmensen LS, Sereikaite V, Jin Z, Fernandes EFA, Wind B, Abalde-Gil F, Daberger J, Vistrup-Parry M, Aguilar-Morante D, Leblanc R, Egea-Jimenez AL, Albrigtsen M, Jensen KE, Jensen TMT, Ivarsson Y, Vincentelli R, Hamerlik P, Andersen JH, Zimmermann P, Lee W, Strømgaard K. Haugaard-Kedström LM, et al. Among authors: egea jimenez al. J Med Chem. 2021 Feb 11;64(3):1423-1434. doi: 10.1021/acs.jmedchem.0c00382. Epub 2021 Jan 27. J Med Chem. 2021. PMID: 33502198
Lipids in Exosome Biology.
Egea-Jimenez AL, Zimmermann P. Egea-Jimenez AL, et al. Handb Exp Pharmacol. 2020;259:309-336. doi: 10.1007/164_2019_220. Handb Exp Pharmacol. 2020. PMID: 31087193
Pharmacological inhibition of syntenin PDZ2 domain impairs breast cancer cell activities and exosome loading with syndecan and EpCAM cargo.
Leblanc R, Kashyap R, Barral K, Egea-Jimenez AL, Kovalskyy D, Feracci M, Garcia M, Derviaux C, Betzi S, Ghossoub R, Platonov M, Roche P, Morelli X, Hoffer L, Zimmermann P. Leblanc R, et al. Among authors: egea jimenez al. J Extracell Vesicles. 2020 Dec;10(2):e12039. doi: 10.1002/jev2.12039. Epub 2020 Dec 15. J Extracell Vesicles. 2020. PMID: 33343836 Free PMC article.
Syntenin-knock out reduces exosome turnover and viral transduction.
Kashyap R, Balzano M, Lechat B, Lambaerts K, Egea-Jimenez AL, Lembo F, Fares J, Meeussen S, Kügler S, Roebroek A, David G, Zimmermann P. Kashyap R, et al. Among authors: egea jimenez al. Sci Rep. 2021 Feb 18;11(1):4083. doi: 10.1038/s41598-021-81697-4. Sci Rep. 2021. PMID: 33602969 Free PMC article.
Syntenin mediates SRC function in exosomal cell-to-cell communication.
Imjeti NS, Menck K, Egea-Jimenez AL, Lecointre C, Lembo F, Bouguenina H, Badache A, Ghossoub R, David G, Roche S, Zimmermann P. Imjeti NS, et al. Among authors: egea jimenez al. Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):12495-12500. doi: 10.1073/pnas.1713433114. Epub 2017 Nov 6. Proc Natl Acad Sci U S A. 2017. PMID: 29109268 Free PMC article.
Tetraspanin-6 negatively regulates exosome production.
Ghossoub R, Chéry M, Audebert S, Leblanc R, Egea-Jimenez AL, Lembo F, Mammar S, Le Dez F, Camoin L, Borg JP, Rubinstein E, David G, Zimmermann P. Ghossoub R, et al. Among authors: egea jimenez al. Proc Natl Acad Sci U S A. 2020 Mar 17;117(11):5913-5922. doi: 10.1073/pnas.1922447117. Epub 2020 Feb 27. Proc Natl Acad Sci U S A. 2020. PMID: 32108028 Free PMC article.
16 results